DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links.
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Protein Aliases: 5' exonuclease Apollo; DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1B protein; PSO2 homolog; SNM1 homolog B; SNMIB
Gene Aliases: APOLLO; DCLRE1B; SNM1B; SNMIB
UniProt ID: (Human) Q9H816
Entrez Gene ID: (Human) 64858