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Product Details
MA5-45962
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3E8
Immunogen
Full Length Human Recombinant Dennd4c protein
Conjugate
Excitation/Emission Max
482/675 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
47.35mM phosphate/2.15mM MES, pH 7.4, with 2mM EDTA, 0.17066µM Pentachlorophenol, 0.8mM ethanol
Contains
no preservative
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2932416
Product Specific Information
A 1:1,000 dilution of MA5-45962 was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.|Detects approximately 213 kDa.
Target Information
DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DENN domain-containing protein 4C; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55)
Gene Aliases: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENND4C; RAB10GEF; RGD1308489
UniProt ID: (Human) Q5VZ89, (Mouse) A6H8H2
Entrez Gene ID: (Human) 55667, (Mouse) 329877, (Rat) 313340
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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