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|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human DKK3 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1/200 - 1/400|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15601 targets DKK3 in FACS and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-15601 immunogen is purified recombinant fragment of human DKK3 expressed in E. Coli.
MA5-15601 detects DKK3 which has a predicted molecular weight of approximately 38kDa.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dickkopf 3 homolog; dickkopf homolog 3; dickkopf-3; dkk-3; DKK3; hDkk-3; regulated in glioma; REIC; RIG; RIG-like 5-6; RIG-like 7-1
DKK3; REIC; RIG; UNQ258/PRO295