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61003S is a mixture of monoclonal antibodies that target Desmoplakin 1/2.
Tumors specifically detected: Primary and metastatic carcinoma and meningioma. Polypeptides reacting: Desmoplakin 1 and 2 (MW 250 000 and 215 000).
Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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