The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
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Protein Aliases: AT225; AT591; DKFZp686J1957; E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; Early growth response protein 1; Early growth response protein 2; EGR-1; EGR-2; FLJ14547; Krox-20 homolog; KROX-20, Drosophila, homolog (early growth response-2); Krox-24 nuclear protein; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-20; Zinc finger protein Krox-24
Gene Aliases: A530045N19Rik; AT225; AT591; CMT1D; CMT4E; egr; Egr-1; Egr-2; EGR1; EGR2; ETR103; G0S30; Krox-1; Krox-20; KROX-24; KROX20; KROX24; Ngf1; NGF1-A; NGF1-B; Ngfi; NGFI-A; NGFIA; TIS8; Zenk; Zfp-25; Zfp-6; ZIF-268; Zif268; ZNF225