Sequence of this protein is as follows: SHQIVPGGRY GVQSFFPEPF VNTLPQARYY NGERTVPQTN GLLSPQQSEE VANPPQRWLV TPVQQPGTNK LDISSYESEY TSSTLLPYGI KSLPLQTSHA LGYYPDPTF
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eomesodermin; Eomesodermin homolog; T-box brain protein 2; T-brain-2
Gene Aliases: EOMES; TBR2
UniProt ID: (Human) O95936