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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15448 targets EphA8 in WB applications and shows reactivity with Human samples.
The MA5-15448 immunogen is purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
EEK; EK3; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; EPH-like kinase 3; EPHA8; Ephrin type-A receptor 8; HEK3; hydroxyaryl-protein kinase; KIAA1459; protein-tyrosine kinase; Tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
EEK; EK3; EPHA8; HEK3; KIAA1459