Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500 | View 9 publications 9 publications |
Immunocytochemistry (ICC/IF) |
- | View 2 publications 2 publications |
ELISA (ELISA) |
Assay-dependent | - |
Immunoprecipitation (IP) |
Assay-dependent | View 3 publications 3 publications |
Miscellaneous PubMed (Misc) |
- | View 2 publications 2 publications |
Product Specifications | |
---|---|
Species Reactivity |
Chicken, Human |
Published species |
Human, Mouse |
Host/Isotype |
Mouse / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1A6C9 |
Immunogen |
A synthetic peptide derived from the C-terminal region of the recombinant EphB2 protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.4 |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2533302 |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cEK5; chicken embryo kinase 5; Developmentally-regulated Eph-related tyrosine kinase; EFL6; EFNB3; EK5; ELK-related tyrosine kinase; embryo kinase 5 protein CEK5; EPH B2; EPH tyrosine kinase 3; EPH-like kinase 5; EphB2/CTF1; EphB2/CTF2; EPHB3; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 2; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPLG8; ETK2; HEK-6; HEK2; LERK8; MGC87492; protein-tyrosine kinase HEK5; Renal carcinoma antigen NY-REN-47; TYRO6; Tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase TYRO5
Gene Aliases: CAPB; CEK5; DRT; EK5; EPHB2; EPHT3; EPTH3; ERK; HEK5; PCBC; TYRO5
UniProt ID: (Human) P29323, (Chicken) P28693
Entrez Gene ID: (Human) 2048, (Chicken) 396513
Molecular Function:
transmembrane signal receptor
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