Product References
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis.
Nature communications
Simó-Riudalbas L,Offner S,Planet E,Duc J,Abrami L,Dind S,Coudray A,Coto-Llerena M,Ercan C,Piscuoglio S,Andersen CL,Bramsen JB,Trono D
MA5-13102 was used in Western Blotting to determine that POU5F1B, in spite of its phylogenetic relationship with the POU5F1/OCT4 transcription factor, is a membrane-enriched protein that associates with protein kinases and known targets or interactors as well as with cytoskeleton-related molecules, and induces intracellular signaling events and the release of trans-acting factors involved in cell growth and cell adhesion.
Sat Aug 20 00:00:00 EDT 2022
Anti-correlation of HER2 and focal adhesion complexes in the plasma membrane.
PloS one
Weinberg F,Han MKL,Dahmke IN,Del Campo A,de Jonge N
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA5-13102) in Immunocytochemistry
Fri Aug 28 00:00:00 EDT 2020
Anti-correlation of HER2 and focal adhesion complexes in the plasma membrane.
PloS one
Weinberg F,Han MKL,Dahmke IN,Del Campo A,de Jonge N
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA5-13102) in Immunocytochemistry
Fri Aug 28 00:00:00 EDT 2020
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cell reports
Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M
MA5-13102 was used in Western Blotting to develop methods for the analysis of extracellular vesicles secreted by macrophages in mouse tumors.
Tue Jun 04 00:00:00 EDT 2019
Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget
Hu S,Sun Y,Meng Y,Wang X,Yang W,Fu W,Guo H,Qian W,Hou S,Li B,Rao Z,Lou Z,Guo Y
MA5-13102 was used in immunoprecipitation and western blot to elucidate the dimerization of ErbB2
Fri Jan 30 00:00:00 EST 2015
Micropapillary component in gastric adenocarcinoma: an aggressive variant associated with poor prognosis.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Zhang Q,Ming J,Zhang S,Li B,Yin L,Qiu X
MA5-13102 was used in immunohistochemistry to study the aggressiveness and poor prognosis of gastric adenocarcinomas with a micropapillary component
Thu Jan 01 00:00:00 EST 2015
EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer.
International journal of cancer
Fichter CD,Timme S,Braun JA,Gudernatsch V,Schöpflin A,Bogatyreva L,Geddert H,Faller G,Klimstra D,Tang L,Hauschke D,Werner M,Lassmann S
MA5-13102 was used in immunocytochemistry and immunohistochemistry to study the value of the expression and dimerization patterns of EGFR, HER2 and HER3 in esophageal cancer histotypes for guiding targeted anti-EGFR and -HER2 therapy
Wed Oct 01 00:00:00 EDT 2014
erbB3 is an active tyrosine kinase capable of homo- and heterointeractions.
Molecular and cellular biology
Steinkamp MP,Low-Nam ST,Yang S,Lidke KA,Lidke DS,Wilson BS
MA5-13102 was used in immunoprecipitation to study the tyrosine kinase activity of erbB3 against a peptide substrate and its ability to participate in erbB2-erbB3 hetero-interactions and erbB3 homo-interactions
Sat Mar 01 00:00:00 EST 2014
Dual HER2 inhibition in combination with anti-VEGF treatment is active in heavily pretreated HER2-positive breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology
Falchook GS,Moulder SL,Wheler JJ,Jiang Y,Bastida CC,Kurzrock R
MA5-13102 was used in immunohistochemistry to study the efficacy of treatment with a combination of trastuzumab, lapatinib and bevacizumab in heavily pretreated patients with metastaic HER2-positive breast cancer
Sun Dec 01 00:00:00 EST 2013
A cell-based screening system for influenza A viral RNA transcription/replication inhibitors.
Scientific reports
Ozawa M,Shimojima M,Goto H,Watanabe S,Hatta Y,Kiso M,Furuta Y,Horimoto T,Peters NR,Hoffmann FM,Kawaoka Y
MA5-13102 was used in western blot to develop a cell-based screening system to identify compounds that inhibit influenza A viral RNA transcription/replication
Mon Sep 30 00:00:00 EDT 2013
Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX®) and the PAM50 breast cancer intrinsic Classifier™ in early-stage estrogen receptor-positive breast cancer.
The oncologist
Kelly CM,Bernard PS,Krishnamurthy S,Wang B,Ebbert MT,Bastien RR,Boucher KM,Young E,Iwamoto T,Pusztai L
MA5-13102 was used in immunohistochemistry to compare the risk assessment in early ER-positive breast cancer as determined using the PAM50 breast cancer intrinsic Classifier and Oncotype DX methodologies
Tue Oct 23 00:00:00 EDT 2012
SGK3 is associated with estrogen receptor expression in breast cancer.
Breast cancer research and treatment
Xu J,Wan M,He Q,Bassett RL,Fu X,Chen AC,Shi F,Creighton CJ,Schiff R,Huo L,Liu D
MA5-13102 was used in immunohistochemistry to study the role of SGK3 in breast cancer and its association with estrogen receptor expression
Sun Jul 01 00:00:00 EDT 2012
The atypical histone macroH2A1.2 interacts with HER-2 protein in cancer cells.
The Journal of biological chemistry
Li X,Kuang J,Shen Y,Majer MM,Nelson CC,Parsawar K,Heichman KA,Kuwada SK
MA5-13102 was used in immunoprecipitation to study the interaction of histone macroH2A1.2 with HER-2 protein in cancer cells and the significance for tumorigenicity
Fri Jun 29 00:00:00 EDT 2012
HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications.
Archives of pathology & laboratory medicine
Hechtman JF,Polydorides AD
MA5-13102 was used in immunohistochemistry to review the literature on HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma
Fri Jun 01 00:00:00 EDT 2012
Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapy.
Annals of oncology : official journal of the European Society for Medical Oncology
Giordano A,Giuliano M,De Laurentiis M,Arpino G,Jackson S,Handy BC,Ueno NT,Andreopoulou E,Alvarez RH,Valero V,De Placido S,Hortobagyi GN,Reuben JM,Cristofanilli M
MA5-13102 was used in immunohistochemistry to study the predictive value of circulating tumor cells in subtypes of metastatic breast cancer
Tue May 01 00:00:00 EDT 2012
NRF2 inhibition represses ErbB2 signaling in ovarian carcinoma cells: implications for tumor growth retardation and docetaxel sensitivity.
Free radical biology & medicine
Manandhar S,Choi BH,Jung KA,Ryoo IG,Song M,Kang SJ,Choi HG,Kim JA,Park PH,Kwak MK
MA5-13102 was used in western blot to study the role of the NRF2 transcription factor in the growth and docetaxel sensitivity of ovarian carcinoma cells
Tue May 01 00:00:00 EDT 2012
Stromal caveolin-1 expression in breast carcinoma. Correlation with early tumor recurrence and clinical outcome.
Pathology oncology research : POR
El-Gendi SM,Mostafa MF,El-Gendi AM
MA5-13102 was used in immunohistochemistry to study the prognostic value of stromal caveolin-1 in breast cancer
Sun Apr 01 00:00:00 EDT 2012
Clinicopathologic features of the mixed epithelial and mesenchymal type metaplastic breast carcinoma with myoepithelial differentiation in a subset of six cases.
Pathology, research and practice
Yigit S,Pehlivan FS,Evcim G,Etit D
MA5-13102 was used in immunohistochemistry to study six cases of mixed epithelial and mesenchymal type metaplastic breast carcinoma with myoepithelial differentiation
Thu Mar 15 00:00:00 EDT 2012
Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.
British journal of neurosurgery
Abdelzaher E,El-Gendi SM,Yehya A,Gowil AG
MA5-13102 was used in immunohistochemistry to identify biomarkers that predict the recurrence of benign meningiomas
Thu Dec 01 00:00:00 EST 2011
Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival.
Archives of gynecology and obstetrics
Ege CB,Akbulut M,Zekioğlu O,Ozdemir N
MA5-13102 was used in immunohistochemistry to investigate the effect of galectin-3 and heparanase on the pathogenesis of endometrial carcinomas
Tue Nov 01 00:00:00 EDT 2011
Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro.
Chemico-biological interactions
Fernand VE,Losso JN,Truax RE,Villar EE,Bwambok DK,Fakayode SO,Lowry M,Warner IM
MA5-13102 was used in western blot to study the effects of rhein, a naturally ocurring quinine, on endothelial and cancer cells under hypoxic conditions
Fri Jul 15 00:00:00 EDT 2011
Low Level of Her-2 Locus Amplification by Fluorescent In Situ Hybridization Does Not Correlate with Her-2 Protein Overexpression by Immunohistochemistry in Barrett's Esophagus.
Journal of oncology
Rygiel AM,Milano F,Ten Kate FJ,Bergman JJ,Krishnadath KK
MA5-13102 was used in immunohistochemistry to study the correlation of Her-2 locus amplification with Her-2 protein overexpression in patients with Barrett's esophagus and esophageal adenocarcinoma
Thu Jul 14 00:00:00 EDT 2011
Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44⁺CD24lo cancer stem cell phenotype.
European journal of cancer (Oxford, England : 1990)
Reuben JM,Lee BN,Gao H,Cohen EN,Mego M,Giordano A,Wang X,Lodhi A,Krishnamurthy S,Hortobagyi GN,Cristofanilli M,Lucci A,Woodward WA
MA5-13102 was used in immunohistochemistry to investigate the presence of cells with a cancer stem cell phenotype in the bone marrow of patients with primary breast cancer.
Fri Jul 01 00:00:00 EDT 2011
Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.
Breast cancer research : BCR
DeFazio-Eli L,Strommen K,Dao-Pick T,Parry G,Goodman L,Winslow J
MA5-13102 was used in immunoprecipitation to investigate the state of HER1-HER2 interaction and modification in cell lines and tumors
Fri Apr 15 00:00:00 EDT 2011
Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast.
Cancer
Kuerer HM,Buzdar AU,Mittendorf EA,Esteva FJ,Lucci A,Vence LM,Radvanyi L,Meric-Bernstam F,Hunt KK,Symmans WF
MA5-13102 was used in immunohistochemistry to investigate the therapeutic benefit of preoperative trastuzumab treatment in ductal carcinoma in situ
Sat Jan 01 00:00:00 EST 2011
Structure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine.
Journal of molecular biology
Fisher RD,Ultsch M,Lingel A,Schaefer G,Shao L,Birtalan S,Sidhu SS,Eigenbrot C
MA5-13102 was used in western blot to determine the X-ray crystal structure of a HER2-antibody paratope complex
Fri Sep 10 00:00:00 EDT 2010
GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer.
Breast cancer research and treatment
Arias-Pulido H,Royce M,Gong Y,Joste N,Lomo L,Lee SJ,Chaher N,Verschraegen C,Lara J,Prossnitz ER,Cristofanilli M
MA5-13102 was used in immunohistochemistry to investigate the GPR30 and estrogen receptor expression in breast cancer
Sun Aug 01 00:00:00 EDT 2010
Comparison of central HER2 testing with quantitative total HER2 expression and HER2 homodimer measurements using a novel proximity-based assay.
American journal of clinical pathology
Huang W,Reinholz M,Weidler J,Yolanda L,Paquet A,Whitcomb J,Lingle W,Jenkins RB,Chen B,Larson JS,Tan Y,Sherwood T,Bates M,Perez EA
MA5-13102 was used in ELISA to develop and evaluate a novel proximity-based assay for quantitating total HER2 expression and HER2 homodimer
Sun Aug 01 00:00:00 EDT 2010
Detection of minimal residual disease in blood and bone marrow in early stage breast cancer.
Cancer
Krishnamurthy S,Cristofanilli M,Singh B,Reuben J,Gao H,Cohen EN,Andreopoulou E,Hall CS,Lodhi A,Jackson S,Lucci A
MA5-13102 was used in immunohistochemistry to study the presence of circulating tumor cells in blood and disseminated tumor cells in bone marrow of women with early stage breast cancer
Thu Jul 15 00:00:00 EDT 2010
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Journal of translational medicine
Norell H,Poschke I,Charo J,Wei WZ,Erskine C,Piechocki MP,Knutson KL,Bergh J,Lidbrink E,Kiessling R
MA5-13102 was used in immunohistochemistry to study the therapeutic potential of HER-2/neu vaccination plus low doses of GM-CSF and IL-2 in metastatic breast carcinoma
Mon Jun 07 00:00:00 EDT 2010
Selective cytotoxicity to HER2-positive tumor cells by a recombinant e23sFv-TD-tBID protein containing a furin cleavage sequence.
Clinical cancer research : an official journal of the American Association for Cancer Research
Wang F,Ren J,Qiu XC,Wang LF,Zhu Q,Zhang YQ,Huan Y,Meng YL,Yao LB,Chen SY,Xu YM,Yang AG
MA5-13102 was used in western blot to study the selective cytotoxicity against HER2-bearing tumors of a recombinant anti-HER2 antibody fragement-Bid fusion protein containing a furin cleavage sequence
Thu Apr 15 00:00:00 EDT 2010
Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.
Clinical cancer research : an official journal of the American Association for Cancer Research
Williams MD,Roberts DB,Kies MS,Mao L,Weber RS,El-Naggar AK
MA5-13102 was used in immunohistochemistry to characterize expression of HER-2 and EFGR genes in salivary duct carcinoma
Thu Apr 15 00:00:00 EDT 2010
Immunohistochemical characterization of subtypes of male breast carcinoma.
Breast cancer research : BCR
Ge Y,Sneige N,Eltorky MA,Wang Z,Lin E,Gong Y,Guo M
MA5-13102 was used in immunohistochemistry to study the immunohistochemistry of subtypes of male breast carcinoma.
Mon Jan 18 00:00:00 EST 2010
Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment.
Cell cycle (Georgetown, Tex.)
Zheng J,Mercado-Uribe I,Rosen DG,Chang B,Liu P,Yang G,Malpica A,Naora H,Auersperg N,Mills GB,Bast RC,Liu J
MA5-13102 was used in immunohistochemistry to study the effect of HER2/neu and a peritoneal microenvironment on the transformation of human ovarian surface epithelial cells into papillary carcinoma
Fri Jan 01 00:00:00 EST 2010
Novel strategies to augment genetically delivered immunotoxin molecular therapy for cancer therapy.
Cancer gene therapy
Liu X,Wu J,Zhang S,Li C,Huang Q
MA5-13102 was used in western blot to evaluate the efficacy of a novel genetic immunotoxin delivery approach for immunotoxin molecular therapy
Sun Nov 01 00:00:00 EDT 2009
HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats.
Journal of feline medicine and surgery
Misirlioglu D,Nak D,Ozyigit MO,Nak Y,Akkoc A
MA5-13102 was used in immunohistochemistry to study the HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats
Thu Oct 01 00:00:00 EDT 2009
Performance of chromogenic in situ hybridization on testing HER2 Status in breast carcinomas with chromosome 17 polysomy and equivocal (2+) herceptest results: a study of two institutions using the conventional and new ASCO/CAP scoring criteria.
American journal of clinical pathology
Gong Y,Sweet W,Duh YJ,Greenfield L,Tarco E,Trivedi S,Symmans WF,Isola J,Sneige N
MA5-13102 was used in immunohistochemistry to evaluate CISH and FISH for measuring HER2 status in breast carcinoma using the conventional and new ASCO/CAP scoring criteria
Sat Aug 01 00:00:00 EDT 2009
Even low-level HER2 expression may be associated with worse outcome in node-positive breast cancer.
The American journal of surgical pathology
Gilcrease MZ,Woodward WA,Nicolas MM,Corley LJ,Fuller GN,Esteva FJ,Tucker SL,Buchholz TA
MA5-13102 was used in immunohistochemistry to study the association of even low-level HER2 expression with poor outcome in node-positive breast cancer
Fri May 01 00:00:00 EDT 2009
Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the number of inconclusive cases.
Archives of pathology & laboratory medicine
Middleton LP,Price KM,Puig P,Heydon LJ,Tarco E,Sneige N,Barr K,Deavers MT
MA5-13102 was used in immunohistochemistry to study the clinical outcomes of HER2 testing after implementation of ASCO/CAP guideline recommendations
Fri May 01 00:00:00 EDT 2009
A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue.
Diagnostic molecular pathology : the American journal of surgical pathology, part B
Shi Y,Huang W,Tan Y,Jin X,Dua R,Penuel E,Mukherjee A,Sperinde J,Pannu H,Chenna A,DeFazio-Eli L,Pidaparthi S,Badal Y,Wallweber G,Chen L,Williams S,Tahir H,Larson J,Goodman L,Whitcomb J,Petropoulos C,Winslow J
MA5-13102 was used in immunocytochemistry to develop a novel proximity assay for detecting HER proteins and homodimers in formalin-fixed cell lines and breast tumor tissues
Sun Mar 01 00:00:00 EST 2009
Triple receptor-negative breast cancer: the effect of race on response to primary systemic treatment and survival outcomes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Dawood S,Broglio K,Kau SW,Green MC,Giordano SH,Meric-Bernstam F,Buchholz TA,Albarracin C,Yang WT,Hennessy BT,Hortobagyi GN,Gonzalez-Angulo AM
MA5-13102 was used in immunohistochemistry to investigate the effect of race on the therapeutic outcome from the treatment of triple receptor-negative breast cancer
Sat Jan 10 00:00:00 EST 2009
Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Journal of cancer research and clinical oncology
Strumane K,Rygiel T,van der Valk M,Collard JG
MA5-13102 was used in western blot to study the role of tiam1 in mammary tumor formation in MMTV-c-neu and MMTV-c-myc mice
Thu Jan 01 00:00:00 EST 2009
Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033.
Cancer biology & therapy
Dilworth JT,Wojtkowiak JW,Mathieu P,Tainsky MA,Reiners JJ,Mattingly RR,Hancock CN
MA5-13102 was used in western blot to study the effect of pan-ErbB inhibitor C1-1033 on the proliferation of NF1 malignant peripheral nerve sheath tumor cell lines
Mon Dec 01 00:00:00 EST 2008
Loss of annexin A1 expression in breast cancer progression.
Applied immunohistochemistry & molecular morphology : AIMM
Cao Y,Li Y,Edelweiss M,Arun B,Rosen D,Resetkova E,Wu Y,Liu J,Sahin A,Albarracin CT
MA5-13102 was used in immunohistochemistry to study ANXA1 expression during the progression of breast carcinomas
Mon Dec 01 00:00:00 EST 2008
Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL.
Cancer research
Van Schaeybroeck S,Kelly DM,Kyula J,Stokesberry S,Fennell DA,Johnston PG,Longley DB
MA5-13102 was used in western blot to investigate the mechanism of acute resistance to TRAIL treatment
Wed Oct 15 00:00:00 EDT 2008
Prognostic significance of HER-2 status in women with inflammatory breast cancer.
Cancer
Dawood S,Broglio K,Gong Y,Yang WT,Cristofanilli M,Kau SW,Meric-Bernstam F,Buchholz TA,Hortobagyi GN,Gonzalez-Angulo AM
MA5-13102 was used in immunohistochemistry to investigate the prognostic value of HER-2 expression in women with inflammatory breast cancer
Thu May 01 00:00:00 EDT 2008
Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent.
Molecular cancer research : MCR
Pedersen NM,Madshus IH,Haslekås C,Stang E
MA5-13102 was used in western blot to study the mechanism of Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane
Sat Mar 01 00:00:00 EST 2008
HER2 expression and efficacy of preoperative paclitaxel/FAC chemotherapy in breast cancer.
Breast cancer research and treatment
Andre F,Mazouni C,Liedtke C,Kau SW,Frye D,Green M,Gonzalez-Angulo AM,Symmans WF,Hortobagyi GN,Pusztai L
MA5-13102 was used in immunohistochemistry to study the correlation between HER2 expression and pathologic complete response to paclitaxel/FAC preoperative chemotherapy in breast cancer
Sat Mar 01 00:00:00 EST 2008
Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism.
Proteins
Hu S,Zhu Z,Li L,Chang L,Li W,Cheng L,Teng M,Liu J
MA5-13102 was used in western blot to study the tumor inhibitory mechanism of an anti-ErbB2 antibody
Fri Feb 15 00:00:00 EST 2008
Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44.
Cancer research
Golshani R,Lopez L,Estrella V,Kramer M,Iida N,Lokeshwar VB
MA5-13102 was used in western blot to investigate the effect of hyaluronic acid synthase-1 on bladder cancer development
Tue Jan 15 00:00:00 EST 2008
Primary neuroendocrine carcinoma of the breast: a case report.
Tumori
Yaren A,Kelten C,Akbulut M,Teke Z,Duzcan E,Erdem E
MA5-13102 was used in immunohistochemistry to report on a case of primary neuroendocrine carcinoma of the breast
Tue Dec 11 00:00:00 EST 2007
Abundance and localization of skeletal muscle-related erbB2 may stimulate tumour growth during initial stages of oral oncogenesis.
Journal of musculoskeletal & neuronal interactions
Vairaktaris E,Moulavassili P,Loukeri S,Spyridonidou S,Yapijakis C,Vassiliou S,Nkenke E,Vylliotis A,Papakosta V,Lazaris A,Patsouris E
MA5-13102 was used in immunohistochemistry to study the role of skeletal muscle-related erbB2 in stimulating tumor growth in oral oncogenesis
Wed Oct 17 00:00:00 EDT 2007
[An analysis of genetic transmission in a father and son with osteosarcoma].
Acta orthopaedica et traumatologica turcica
Tokatli F,Alas RC,Altaner S,Pala F,Uygun K,Uzal C,Yalniz E
MA5-13102 was used in immunohistochemistry to report on a case of a father and son with familial osteosarcoma
Fri Jul 20 00:00:00 EDT 2007
Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study.
The Lancet. Oncology
Gong Y,Yan K,Lin F,Anderson K,Sotiriou C,Andre F,Holmes FA,Valero V,Booser D,Pippen JE,Vukelja S,Gomez H,Mejia J,Barajas LJ,Hess KR,Sneige N,Hortobagyi GN,Pusztai L,Symmans WF
MA5-13102 was used in immunohistochemistry to develop a method for profiling oestrogen-receptor status and ERBB2 status in breast carcinoma
Thu Mar 01 00:00:00 EST 2007
Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy.
Cancer
Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M
MA5-13102 was used in immunohistochemistry to study the value of serum HER-2 receptor extracellular domain measurements for predicting the response to chemotherapy in primary breast cancer patients
Thu Feb 01 00:00:00 EST 2007
An acetylation site in the middle domain of Hsp90 regulates chaperone function.
Molecular cell
Scroggins BT,Robzyk K,Wang D,Marcu MG,Tsutsumi S,Beebe K,Cotter RJ,Felts S,Toft D,Karnitz L,Rosen N,Neckers L
MA5-13102 was used in western blot to study the functional consequences of Hsp90 acetylation
Fri Jan 12 00:00:00 EST 2007
Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications.
Journal of cutaneous pathology
Nash JW,Barrett TL,Kies M,Ross MI,Sneige N,Diwan AH,Lazar AJ
MA5-13102 was used in immunohistochemistry to demonstrate the amplification of Her-2/neu gene in metastatic hidradenocarcinoma by fluorescence in situ hybridization
Mon Jan 01 00:00:00 EST 2007
MUC4 expression and its relation to ErbB2 expression, apoptosis, proliferation, differentiation, and tumor stage in non-small cell lung cancer (NSCLC).
Pathology, research and practice
Karg A,Dinç ZA,Başok O,Uçvet A
MA5-13102 was used in immunohistochemistry to study the expression of MUC4 in different stages of non-small cell lung cancer and its relationship with ErbB2 expression
Thu Sep 21 00:00:00 EDT 2006
Constitutive neuregulin-1/ErbB signaling contributes to human vestibular schwannoma proliferation.
Glia
Hansen MR,Roehm PC,Chatterjee P,Green SH
MA5-13102 was used in western blot to study the role of constitutive neuregulin-1/ErbB signaling in human vestibular schwannoma proliferation
Sat Apr 15 00:00:00 EDT 2006
A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding.
Endocrine-related cancer
Symmans WF,Fiterman DJ,Anderson SK,Ayers M,Rouzier R,Dunmire V,Stec J,Valero V,Sneige N,Albarracin C,Wu Y,Ross JS,Wagner P,Theriault RL,Arun B,Kuerer H,Hess KR,Zhang W,Hortobagyi GN,Pusztai L
MA5-13102 was used in immunohistochemistry to study the diagnostic marker of breast cancers associated with immature cell type
Thu Dec 01 00:00:00 EST 2005
Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells.
Cancer research
Kassouf W,Dinney CP,Brown G,McConkey DJ,Diehl AJ,Bar-Eli M,Adam L
MA5-13102 was used in western blot to study the mechanism of resistance to the EGFR tyrosine kinase inhibitor Gefitinib in bladder cancer cells
Tue Nov 15 00:00:00 EST 2005
Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow.
Clinical & experimental metastasis
Cabioglu N,Sahin A,Doucet M,Yavuz E,Igci A,O Yildirim E,Aktas E,Bilgic S,Kiran B,Deniz G,Price JE
MA5-13102 was used in immunohistochemistry to study CXCR4 receptor expression in breast cancer as a predictive marker for isolated tumor cells in bone marrow
Tue Oct 18 00:00:00 EDT 2005
Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Van Schaeybroeck S,Karaiskou-McCaul A,Kelly D,Longley D,Galligan L,Van Cutsem E,Johnston P
MA5-13102 was used in western blot to investigate the effect of gefitinib on epidermal growth factor receptor phosphorylation and its prognostic significance
Sat Oct 15 00:00:00 EDT 2005
Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Diaz LK,Cristofanilli M,Zhou X,Welch KL,Smith TL,Yang Y,Sneige N,Sahin AA,Gilcrease MZ
MA5-13102 was used in immunohistochemistry to study the relationship between beta4 integrin subunit expression and early breast tumor size and nuclear grade
Thu Sep 01 00:00:00 EDT 2005
CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Cabioglu N,Yazici MS,Arun B,Broglio KR,Hortobagyi GN,Price JE,Sahin A
MA5-13102 was used in immunohistochemistry to investigate CCR7 and CXCR4 as diagnostic markers for axillary lymph node metastasis in T1 breast cancer
Mon Aug 15 00:00:00 EDT 2005
Cooperative interactions of HER-2 and HPV-16 oncoproteins in the malignant transformation of human mammary epithelial cells.
Neoplasia (New York, N.Y.)
Woods Ignatoski KM,Dziubinski ML,Ammerman C,Ethier SP
MA5-13102 was used in immunoprecipitation to investigate the interaction between HER-2 and HPV-16 in human mammary epithelial cells during malignant transformation
Mon Aug 01 00:00:00 EDT 2005
CD44 expression is associated with increased survival in node-negative invasive breast carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Diaz LK,Zhou X,Wright ET,Cristofanilli M,Smith T,Yang Y,Sneige N,Sahin A,Gilcrease MZ
MA5-13102 was used in immunohistochemistry to study the prognostic significance of CD44 expression in node-negative invasive breast carcinoma
Sun May 01 00:00:00 EDT 2005
Expression, location, and interactions of ErbB2 and its intramembrane ligand Muc4 (sialomucin complex) in rat mammary gland during pregnancy.
Journal of cellular physiology
Price-Schiavi SA,Andrechek E,Idris N,Li P,Rong M,Zhang J,Carothers Carraway CA,Muller WJ,Carraway KL
MA5-13102 was used in immunohistochemistry and western blot to study the role of ErbB2 and its intramembrane ligand Muc4 in rat mammary gland during pregnancy
Fri Apr 01 00:00:00 EST 2005
Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures.
Journal of neurochemistry
Zhang L,Fletcher-Turner A,Marchionni MA,Apparsundaram S,Lundgren KH,Yurek DM,Seroogy KB
MA5-13102 was used in western blot to study the potential neurotrophic and neuroprotective effects of the GGF-2 on rat dopaminergic neurons
Wed Dec 01 00:00:00 EST 2004
Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2.
Cancer cell
Wang SC,Lien HC,Xia W,Chen IF,Lo HW,Wang Z,Ali-Seyed M,Lee DF,Bartholomeusz G,Ou-Yang F,Giri DK,Hung MC
MA5-13102 was used in EMSA to investigate the influence of ErbB-2 on COX-2 expression and its mechanism
Wed Sep 01 00:00:00 EDT 2004
Inability of immunohistochemistry to predict clinical outcomes of endometrial cancer patients.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Gossett DR,Alo P,Bristow RE,Galati M,Kyshtoobayeva A,Fruehauf J,Montz FJ
MA5-13102 was used in immunohistochemistry to study the inability of immunohistochemistry to predict clinical outcome in endometrial cancer
Thu May 27 00:00:00 EDT 2004
Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expression.
The Journal of biological chemistry
Yang G,Cai KQ,Thompson-Lanza JA,Bast RC,Liu J
MA5-13102 was used in immunohistochemistry to study the role of Her-2/neu in breast and ovarian tumorigenesis
Fri Feb 06 00:00:00 EST 2004
Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma.
Cancer
Esteva FJ,Sahin AA,Smith TL,Yang Y,Pusztai L,Nahta R,Buchholz TA,Buzdar AU,Hortobagyi GN,Bacus SS
MA5-13102 was used in immunohistochemistry to study the prognostic value of p38 mitogen-activated protein kinase phosphorylation and HER-2 in lymph node-positive breast carcinoma
Sun Feb 01 00:00:00 EST 2004
In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer.
Gynecologic oncology
Cloven NG,Kyshtoobayeva A,Burger RA,Yu IR,Fruehauf JP
MA5-13102 was used in immunohistochemistry to study whether there is a relationship between histologic subtype of epithelial ovarian cancer and chemoresistance
Thu Jan 01 00:00:00 EST 2004
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Esteva FJ,Sahin AA,Rassidakis GZ,Yuan LX,Smith TL,Yang Y,Gilcrease MZ,Cristofanilli M,Nahta R,Pusztai L,Claret FX
MA5-13102 was used in immunohistochemistry to study the prognostic significance of JAB1 and p27(Kip1) in node-negative breast cancer.
Sat Nov 15 00:00:00 EST 2003
Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features.
Cancer
Middleton LP,Amin M,Gwyn K,Theriault R,Sahin A
MA5-13102 was used in immunohistochemistry to study the histopathology and immunohistochemistry of breast carcinoma in pregnant women
Mon Sep 01 00:00:00 EDT 2003
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
The Journal of biological chemistry
Ramsauer VP,Carraway CA,Salas PJ,Carraway KL
MA5-13102 was used in immunocytochemistry to investigate the translocation of ErbB2 to the apical surface in polarized epithelial cells
Fri Aug 08 00:00:00 EDT 2003
Mucin-rich variant of salivary duct carcinoma: a clinicopathologic and immunohistochemical study of four cases.
The American journal of surgical pathology
Simpson RH,Prasad AR,Lewis JE,Skálová A,David L
MA5-13102 was used in immunohistochemistry to study the clinicopathology and immunohistochemistry of four cases of mucin-rich variant of salivary duct carcinoma
Fri Aug 01 00:00:00 EDT 2003
Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215.
FEBS letters
Vadlamudi RK,Sahin AA,Adam L,Wang RA,Kumar R
MA5-13102 was used in western blot to study the ability of heregulin and HER2 signaling to upregulate c-Src tyrosine 215 phosphoylation and subsequently upregulate FAK tyrosine 861 phosphorylation in breast cancer cells
Thu May 22 00:00:00 EDT 2003
Her2/neu overexpression in differentiated thyroid carcinomas predicts metastatic disease.
Virchows Archiv : an international journal of pathology
Kremser R,Obrist P,Spizzo G,Erler H,Kendler D,Kemmler G,Mikuz G,Ensinger C
MA5-13102 was used in immunohistochemistry to study the prognostic value of Her2/neu overexpression in differentiated thyroid carcinomas
Tue Apr 01 00:00:00 EST 2003
MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions.
The Journal of biological chemistry
Talukder AH,Mishra SK,Mandal M,Balasenthil S,Mehta S,Sahin AA,Barnes CJ,Kumar R
MA5-13102 was used in western blot to study the interaction of MTA1 with MAT1 and its role in regulating estrogen receptor transactivation functions
Fri Mar 28 00:00:00 EST 2003
Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response.
Clinical cancer research : an official journal of the American Association for Cancer Research
Davis DW,Buchholz TA,Hess KR,Sahin AA,Valero V,McConkey DJ
MA5-13102 was used in immunohistochemistry to study whether early assessment of apoptosis following breast cancer neoadjuvant chemotherapy predicts clinical response
Sat Mar 01 00:00:00 EST 2003
Alpha6beta1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells.
Oncogene
Shimizu H,Seiki T,Asada M,Yoshimatsu K,Koyama N
MA5-13102 was used in western blot to study the role of alpha6beta1 integrin in inducing proteasome-mediated cleavage of erbB2 in breast cancer cells
Thu Feb 13 00:00:00 EST 2003
Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Verschraegen CF,Hu W,Du Y,Mendoza J,Early J,Deavers M,Freedman RS,Bast RC,Kudelka AP,Kavanagh JJ,Giovanella BC
MA5-13102 was used in immunocytochemistry to characterize cell cultures and xenografts derived from patients with ovarian cancer
Sat Feb 01 00:00:00 EST 2003
Metalloproteinases stimulate ErbB-dependent ERK signaling in human skin organ culture.
The Journal of biological chemistry
Stoll SW,Kansra S,Elder JT
MA5-13102 was used in immunoprecipitation and western blot to study the role of MMPs in stimulating ErbB-dependent ERK signaling in human skin organ culture
Fri Jul 26 00:00:00 EDT 2002
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Esteva FJ,Valero V,Booser D,Guerra LT,Murray JL,Pusztai L,Cristofanilli M,Arun B,Esmaeli B,Fritsche HA,Sneige N,Smith TL,Hortobagyi GN
MA5-13102 was used in immunohistochemistry to study the clinical effect of a docetaxel and trastuzumab combination treatment in HER-2-overexpressing metastatic breast cancer
Mon Apr 01 00:00:00 EST 2002
Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ.
Cancer research
Half E,Tang XM,Gwyn K,Sahin A,Wathen K,Sinicrope FA
MA5-13102 was used in immunohistochemistry to study the expression of COX-2 in human breast cancers and adjacent ductal carcinoma in situ
Fri Mar 15 00:00:00 EST 2002
Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes.
Neoplasia (New York, N.Y.)
Stoll SW,Kansra S,Peshick S,Fry DW,Leopold WR,Wiesen JF,Sibilia M,Zhang T,Werb Z,Derynck R,Wagner EF,Elder JT
MA5-13102 was used in immunocytochemistry, immunoprecipitation, and western blot to study the differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes
Tue Dec 04 00:00:00 EST 2001
Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells.
International journal of radiation oncology, biology, physics
Lammering G,Lin PS,Contessa JN,Hampton JL,Valerie K,Schmidt-Ullrich RK
MA5-13102 was used in western blot to study the use of adenovirus-mediated overexpression of dominant negative EGFR to radiosensitize human carcinoma and malignant glioma cells
Thu Nov 01 00:00:00 EST 2001
Tyrphostin AG825 triggers p38 mitogen-activated protein kinase-dependent apoptosis in androgen-independent prostate cancer cells C4 and C4-2.
Cancer research
Murillo H,Schmidt LJ,Tindall DJ
MA5-13102 was used in western blot to study the role of p38 MAP kinase in the induction of apoptosis in androgen-independent prostate cancer cells by the EGFR inhibitor typhostin AG825
Mon Oct 15 00:00:00 EDT 2001
transmembrane signal receptor
