|ELISA (ELISA)||0.1-1.0 ug/ml|
|Flow Cytometry (Flow)||1:20|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20-1:200|
|Immunoprecipitation (IP)||2-5 ug|
|Western Blot (WB)||2 ug/ml|
|Western Blot (WB)||See 1 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Bovine, Chicken, Guinea pig, Human, Mouse, Rat|
|Published species reactivity||Rabbit Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Bovine FGF Receptor 1 (flg) purified from bovine Coronary Venular Endothelial Cells (CVEC).|
|Contains||0.1% sodium azide|
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Basic fibroblast growth factor receptor 1; bFGF-R; bFGF-R-1; BFGFR; c-fgr; CD331; cek1 protein; FGF receptor-1; FGFR-1; FGFR1/PLAG1 fusion; Fibroblast Growth Factor Receptor 1; FLT-2; FMS-like tyrosine kinase 2; Fms-like tyrosine kinase-2; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; hydroxyaryl-protein kinase; MFR; N-sam; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Gene Aliases: AW208770; bFGF-R-1; BFGFR; c-fgr; CD331; CEK; CEK1; Eask; ECCL; FGFBR; FGFR-1; FGFR1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; Hspy; KAL2; MFR; N-SAM; OGD
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