|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (480 ELQAQPGTPQDSPL 493) of FOXN1/Hfh11 protein.|
|Storage buffer||whole serum with 50% glycerol|
|Contains||0.025% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
FOXN1 is a 648 amino acid protein belongs to winged helix/forkhead family containing 1 fork-head DNA-binding domain and is a transcriptional regulator involved in development. It is involved in directing lineage choices of multi-potential progenitor epithelial cells and controls important regulating genes of lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicle and nail apparatus and its defects leads to T-cell immunodeficiency congenital alopecia, nail dystrophy, macroscopic nudity and an inborn dysgenesis of the thymus. It is expressed in hair follicles, skin and nail apparatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.