|Immunocytochemistry (ICC)||1-2 µg/ml|
|Immunofluorescence (IF)||1-2 µg/ml|
|Western Blot (WB)||1:500-1:5000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues L N(654) V G N F T G A K Q A S S Q S W V(670) of human FOXO3.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-805 detects FoxO3.
PA1-805 has been successfully used in Western blot procedures. In Western blot analysis of rat heart and lung, this antibody detects a ~ 71 kDa protein representing FoxO3.
The PA1-805 immunogen is a synthetic peptide corresponding to residues L N(654) V G N F T G A K Q A S S Q S W V(670) of human FOXO3. This sequence is conserved in human, mouse, and rat.
FoxO (forkhead box O) proteins are a family of transcription factors characterized by the distinct forkhead domain. The FoxO proteins act in the insulin signaling pathway, but FoxO3 has also been shown to play a role in the regulation of apoptosis, cell cycle progression and cancer. Several splice variants of FoxO3 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AF6q21 protein; FkhR; forkhead box O3A; Forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; Forkhead in rhabdomyosarcoma-like 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
Gene Aliases: 1110048B16Rik; 2010203A17Rik; AF6q21; C76856; Fkhr2; FKHRL1; FKHRL1P2; FOXO2; FOXO3; FOXO3A
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