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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Elephant, Rabbit, Pig (100%); Mouse, Rat, Hamster (93%); Opossum (86%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
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Protein Aliases: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; frizzled homolog 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor
Gene Aliases: C2orf31; FZD5; HFZ5
UniProt ID: (Human) Q13467
Entrez Gene ID: (Human) 7855, (Rabbit) 100352919, (Pig) 100519058, (Dog) 100855544
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