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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 6-60 of human Fgl2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 50 kDa.
Purity is >95% by SDS-PAGE.
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role,such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively xpressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation.Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
associated with MHV-3 induced prothrombinase activity; cytotoxic T-lymphocyte-specific protein; FGL2; fibrinogen-like 2; fibrinogen-like protein 2; fibroleukin; prothrombinase
AI385601; FGL2; Fiblp; musfiblp; pT49; T49