|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, corresponding to the N-terminal extracellular domain of human FSH receptor.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
PA1-23545 detects FSH Receptor in human samples.
PA1-23545 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-23545 immunogen is a synthetic peptide, KLH conjugated, corresponding to the N-terminal extracellular domain of human FSH receptor.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing. FSHR expression has been reported in ovary, uterus, and testis. ESTs have been isolated from testis libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Follicle-stimulating hormone, interleukin-1, and bone density in adult women.
PA1-23545 was used in flow cytometry to investigate the mechanism for the effect of follicle-stimulating hormone on bone loss in women
|Cannon JG,Cortez-Cooper M,Meaders E,Stallings J,Haddow S,Kraj B,Sloan G,Mulloy A||American journal of physiology. Regulatory, integrative and comparative physiology (298:R790)||2010|