Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-32699 detects GPR37 from human samples.
PA1-32699 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32699 immunogen is: Synthetic peptide, KLH conjugated.
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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