MA5-17140 targets NR6A1 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples.
The MA5-17140 immunogen is purified recombinant fragment of human NR6A1 (amino acids: 65-118) expressed in E. Coli.
MA5-17140 detects NR6A1 which has a predicted molecular weight of approximately 54.3kDa.
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
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Protein Aliases: GCNF; Germ cell nuclear factor; germ cell nuclear factor variant 1; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR
Gene Aliases: CT150; GCNF; GCNF1; hGCNF; hRTR; NR61; NR6A1; RTR
UniProt ID: (Human) Q15406
Entrez Gene ID: (Human) 2649