|Tested species reactivity||Human, Mouse, Pig, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Sheep / IgG|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GPR43 Potentiates ß-Cell Function in Obesity.
PA1-85465 was used in immunohistochemistry to investigate how modulation of GPR43 contributes to metabolic disease
|McNelis JC,Lee YS,Mayoral R,van der Kant R,Johnson AM,Wollam J,Olefsky JM||Diabetes (64:3203)||2015|