|Tested species reactivity||Human, Mouse, Non-human primate, Pig, Rabbit, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Partially purified vesicles.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody does not react with dog.
This product requires enzyme-mediated antigen retrieval prior to staining of paraffin sections. Proteinase K is recommended.
The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 (Glucose transporter type 4, insulin-responsive) glucose transporter from intracellular storage sites to the cell surface. Insulin stimulates glucose transport by promoting translocation of GLUT4 proteins from the perinuclear compartment to the cell surface. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.