|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Clone||GH01/2 + GH02/7|
|Immunogen||Purified recombinant human growth hormone|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:2000-1:4000|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MA5-11926 targets Growth Hormone Human in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-11926 immunogen is purified recombinant human growth hormone.
hGH is produced by the somatotroph cells in the pituitary. hGH acts through binding to membrane receptors that belong to the cytokine receptor superfamily. Ligand binding induces receptor dimerization and activation of the receptor-associated kinase: JAK2; this results in phosphorylation of the kinase itself, of the receptor, and of many cellular proteins including the Stat proteins as well as adaptors leading to the activation of the Ras/MAP kinase pathway and of the PI-3 kinase pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis.
MA5-11926 was used in western blot to investigate the septin SEPT5 phosphorylation by cyclin-dependent kinase 5 and its effect on exocytosis
|Amin ND,Zheng YL,Kesavapany S,Kanungo J,Guszczynski T,Sihag RK,Rudrabhatla P,Albers W,Grant P,Pant HC||The Journal of neuroscience : the official journal of the Society for Neuroscience (28:3631)||2008|