MA1-23308 detects HEC1 in human, mouse, pig, hamster and African green monkey samples.
MA1-23308 has been successfully used in immunofluorescence, immunoprecipitation, immunohistochemistry, flow cytometry and Western blot procedures. Positive control of HELA WCE suggested.
The MA1-23308 immunogen is partial human HEC1 protein consisting of amino acids 56-642.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Human HEC 1 is a coiled-coil protein that has been demonstrated to have a role in M-phase progression. It is essential for proper chromosome segregation. Its depletion results inthe impairment of chromosome congression and results in spindle checkpoint activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HEC; HEC1; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; Kinetochore protein Hec1; Kinetochore protein NDC80 homolog; Kinetochore-associated protein 2; KNTC2; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; putative kinetochore protein NDC80 like protein; Retinoblastoma-associated protein HEC; TID3
Gene Aliases: 2610020P18Rik; AV139730; HEC; HEC1; HsHec1; hsNDC80; KNTC2; NDC80; TID3