|Tested species reactivity||Bovine, Cat, Human, Non-human primate|
|Published species reactivity||Non-human primate, Human, Not Applicable|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Membrane of human tonsil cells.|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Functional Assay (FN)||Assay Dependent|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody will not cross-react with rabbit.
Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
Purity is >95% by SDS-PAGE.
Western blot should be performed under non-reducing conditions.
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Hepatitis C virus infection in inclusion body myositis: A case-control study.
MA1-19027 was used in immunohistochemistry - paraffin section to determine if there is an association between inclusion body myositis and hepatitis C virus infection
|Uruha A,Noguchi S,Hayashi YK,Tsuburaya RS,Yonekawa T,Nonaka I,Nishino I||Neurology (86:211)||2016|
Interferon-¿ induces immunoproteasomes and the presentation of MHC I-associated peptides on human salivary gland cells.
MA1-19027 was used in immunoprecipitation and western blot to study lactacystin and IFN-gamma in human salivary glands
|Arellano-Garcia ME,Misuno K,Tran SD,Hu S||PloS one (9:null)||2014|
|Not Applicable||Not Cited||
The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICB.
MA1-19027 was used in western blot to report that the human herpesvirus-7 U21 gene product interferes with natural killer cell recognition
|Schneider CL,Hudson AW||PLoS pathogens (7:null)||2011|
Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways.
MA1-19027 was used in immunocytochemistry to study the role of clathrin-dependent and clathrin-independent routes in the uptake of Helicobacter pylori vesicles by gastric epithelial cells
|Olofsson A,Nygård Skalman L,Obi I,Lundmark R,Arnqvist A||mBio (5:e00979)||2014|
|Non-human primate||Not Cited||
Alterations in the Arf6-regulated plasma membrane endosomal recycling pathway in cells overexpressing the tetraspan protein Gas3/PMP22.
MA1-19027 was used in immunocytochemistry to study alterations in Arf6-regulated plasma membrane endosomal recycling in cells overexpressing Gas3/PMP22
|Chies R,Nobbio L,Edomi P,Schenone A,Schneider C,Brancolini C||Journal of cell science (116:987)||2003|
Co-existence of epithelioid and fibroblastoid subsets in a sarcomatoid renal carcinoma cell line revealed by clonal studies.
MA1-19027 was used in flow cytometry to study the presence in a sarcomatoid renal carcinoma cell line of both epithelioid and fibroblastoid cells
|Hsieh CH,Chen HC,Chang YH,Pang ST,Kuo ML,Chuang CK,Liao SK||Anticancer research (33:4875)||2013|
Induction of metastatic cancer stem cells from the NK/LAK-resistant floating, but not adherent, subset of the UP-LN1 carcinoma cell line by IFN-¿.
MA1-19027 was used in flow cytometry to study the induction of metastatic cancer stem cells from UP-LN1 cell line
|Chen HC,Chou AS,Liu YC,Hsieh CH,Kang CC,Pang ST,Yeh CT,Liu HP,Liao SK||Laboratory investigation; a journal of technical methods and pathology (91:1502)||2011|
Establishment of a quantitative ELISA capable of determining peptide - MHC class I interaction.
MA1-19027 was used in ELISA to develop a quantitative ELISA assay for studying peptide-MHC class I interactions
|Sylvester-Hvid C,Kristensen N,Blicher T,Ferré H,Lauemøller SL,Wolf XA,Lamberth K,Nissen MH,Pedersen LØ,Buus S||Tissue antigens (59:251)||2002|