Invitrogen

HOXD10 Monoclonal Antibody (OTI1D11)

View all (14) HOXD10 antibodies

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Protocols

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HOXD10 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a HOXD10 monoclonal antibody (Product # MA5-26485).

HOXD10 Antibody in Western Blot (WB) — Western blot analysis of HOXD10 in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with HOXD10 (Product # MA5-26485) monoclonal antibody.

Product Details

MA5-26485

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500	-
Immunohistochemistry (Paraffin) (IHC (P))	1:150	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Mouse / IgG2b
Class	Monoclonal
Type	Antibody
Clone	OTI1D11
Immunogen	Human recombinant protein fragment corresponding to amino acids 80-340 of HOXD10 produced in E.coli View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Affinity Chromatography
Storage buffer	PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2724472

Target Information

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: d10; homeo box 4D; homeo box D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E; Homeobox protein Hox-D10; Hox-45

Gene Aliases: Hox-4.4; HOX4; HOX4D; HOX4E; HOXD10

UniProt ID: (Human) P28358

Entrez Gene ID: (Human) 3236

Molecular Function: homeodomain transcription factor

Function(s)

transcription, DNA-templated single fertilization skeletal muscle tissue development adult locomotory behavior anterior/posterior pattern specification proximal/distal pattern formation spinal cord motor neuron cell fate specification embryonic limb morphogenesis forelimb morphogenesis hindlimb morphogenesis positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis peripheral nervous system neuron development neuromuscular process

Process(es)

chromatin binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding

HOXD10 Monoclonal Antibody (OTI1D11)

Product Details

MA5-26485

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

RRID

Target Information

References (0)

Bioinformatics

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