Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
Positive test controls include: HeLa, MCF-7, 293T, A-549, NCI-H460, Mouse brain, Mouse lung, Mouse spleen. The target is usually found in the following locations: Nucleus.
Immunogen sequence: MASNKTTLQK MGKKQNGKSK KVEEAEPEEF VVEKVLDRRV VNGKVEYFLK WKGFTDADNT WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA ADKPRGFARG LDPERIIGAT DSSGELMFLM KWKDSDEADL VLAKEANMKC PQIVIAFYEE RLTWHSCPED EAQ
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox protein homolog 3; HECH; heterochromatin protein 1 gamma; Heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; Modifier 2 protein; OTTHUMP00000202463
Gene Aliases: CBX3; HECH; HP1-GAMMA; HP1g; HP1Hs-gamma; M32
UniProt ID: (Human) Q13185
Entrez Gene ID: (Human) 11335, (Mouse) 12417, (Rat) 297093
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