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Product Details
66798-1-IG
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:5,000-1:50,000 | - |
Immunocytochemistry (ICC/IF) |
1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
3F1F5 |
Immunogen |
HPGD Fusion Protein Ag1499 (1-266 aa encoded by BC018986) |
Conjugate |
Unconjugated
|
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MHVNGKVAL VTGAAQGIGR AFAEALLLKG AKVALVDWNL EAGVQCKAAL DEQFEPQKTL FIQCDVADQQ QLRDTFRKVV DHFGRLDILV NNAGVNNEKN WEKTLQINLV SVISGTYLGL DYMSKQNGGE GGIIINMSSL AGLMPVAQQP VYCASKHGIV GFTRSAALAA NLMNSGVRLN AICPGFVNTA ILESIEKEEN MGQYIEYKDH IKDMIKYYGI LDPPLIANGL ITLIEDDALN GAIMKITTSK GIHFQDYDTT PFQAKTQ (1-266 aa encoded by BC018986)
Target Information
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; short chain dehydrogenase/reductase family 36C, member 1
Gene Aliases: 15-PGDH; HPGD; PGDH; PGDH1; PHOAR1; SDR36C1
UniProt ID: (Human) P15428
Entrez Gene ID: (Human) 3248
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
prostaglandin metabolic process
transforming growth factor beta receptor signaling pathway
female pregnancy
parturition
lipoxygenase pathway
ovulation
negative regulation of cell cycle
oxidation-reduction process
thrombin receptor signaling pathway
ductus arteriosus closure
lipoxin metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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