Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Monoclonal antibody HPV-4G3 reacts with HPV-18 E6 peptide. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women and accounts for a high-mortality rate because of its late diagnosis and poor prognosis|Initial establishment and subsequent progression of this form of cancer are completely dependent on two major oncogenes E6 and E7, which are expressed constitutively leading to tumorigenesis|E6 is relatively large protein with 150-160 amino acids coding an 18 kDa protein|It's unique structure has been found to be responsible for the oncogenicity of the protein [PMID: 32038557]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HPV virus E6; HPV virus Protein E6; Human papillomavirus E6; Human papillomavirus Protein E6
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