|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (QLHIMDYNETHHEH) corresponding to the C-terminus amino acids of TSC1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4ug/ml|
|Western Blot (WB)||0.1-0.3 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Regulation of PERK-eIF2¿ signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
PA5-18506 was used in immunocytochemistry and western blot to study the control of homoeostasis and survival of myelinating oligodendrocytes by regulation of PERK-eIF2alpha signaling by tuberous sclerosis complex-1
|Jiang M,Liu L,He X,Wang H,Lin W,Wang H,Yoon SO,Wood TL,Lu QR||Nature communications (7:null)||2016|