|Flow Cytometry (Flow)||1.2 µg/10^6 cells|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||cDNA encoding human ICOSL|
|Storage buffer||PBS, pH 7.2|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody recognizes native human ICOSL protein expressed in transfected mammalian cells.
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B7 homolog 2; B7 homologue 2; B7-like protein Gl50; B7-related protein 1; B7H2; B7RP1; GL50; ICOS Ligand; ICOS-L; ICOSL; inducible T-cell co-stimulator ligand; KIAA0653; transmembrane protein B7-H2 ICOS ligand
Gene Aliases: B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS
Entrez Gene ID: (Human) 23308
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