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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).|
|Purification||Antigen affinity chromatography|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Blocking Assay (BLOCK)||50-200 molar excess|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Neutralization (Neu)||50-200 molar excess|
|Western Blot (WB)||1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with rat and mouse based on 88% sequence homology.
Suggested positive control: antigen standard for CYR61 (transient overexpression lysate), MDA-MB-231 breast cancer cell lysate.
CYR61 is a cysteine-rich, heparin-binding, growth factor belonging to the CCN family of secreted regulatory proteins. It stimulates chondrogensis and angiogenesis, playing an important role in cartilage and bone formation, as well as tumor growth and vascularization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CCN family member 1; CCN1; Cysteine-rich angiogenic induce 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP-10; IGFBP10; insulin-like growth factor-binding protein 10
CCN1; CYR61; GIG1; IGFBP10