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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 273-300 amino acids from the central region of human IL1R2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
antigen CDw121b; beta; CD121 antigen-like family member B; CD121b; IL-1 type II receptor; IL-1R-beta; IL-1RT-2; IL-1RT2; IL1RB; ILR2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; interleukin-1 receptor beta; interleukin-1 receptor type 2; interleukin-1 receptor type II; type II interleukin-1 receptor; type II interleukin-1 receptor, beta
CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2; IL1R2c; IL1RB