Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
Assay-dependent | View 1 publication 1 publication |
Immunohistochemistry (IHC) |
Assay-dependent | - |
Flow Cytometry (Flow) |
Assay-dependent | View 1 publication 1 publication |
ELISA (ELISA) |
Assay-dependent | View 1 publication 1 publication |
Neutralization (Neu) |
Assay-dependent | View 1 publication 1 publication |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rat / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
JES10-5A2 |
Immunogen |
Purified recombinant human IL-13 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
purified |
Storage buffer |
PBS |
Contains |
no preservative |
Storage conditions |
-20°C |
RRID |
AB_2536246 |
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALRH; ALRH antibody; BHR1; il 13; IL-13; ILN; Interleukin; Interleukin-13; Interleukin13; MGC116786; MGC116788; MGC116789; NC30 antibody; P600 antibody
Gene Aliases: IL-13; IL13; NC30; P600
UniProt ID: (Human) P35225
Entrez Gene ID: (Human) 3596
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