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      IL-13 Monoclonal Antibody (JES10-5A2)

      See 31 other IL-13 antibodies ›
      IL-13 Monoclonal Antibody for Western Blot, IHC, Flow, ELISA and Neu

      Catalog#: AHC0132 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      AHC0132 500 µg
      303.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Rat Secondary Antibodies (236)
      Alexa Fluor® Anti-Rat Secondary Antibodies (18)
      HRP Anti-Rat Secondary Antibodies (32)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Published species reactivity Human, Not Applicable
      Host / Isotype Rat / IgG1
      Class Monoclonal
      Type Antibody
      Clone JES10-5A2
      Immunogen Purified recombinant human IL-13
      Conjugate Unconjugated
      Form Liquid
      Purification purified
      Storage buffer PBS
      Contains no preservative
      Storage Conditions -20°C
      Tested Applications Dilution *
      ELISA (ELISA) Assay Dependent
      Flow Cytometry (Flow) Assay Dependent
      Immunohistochemistry (IHC) Assay Dependent
      Neutralization (Neu) Assay Dependent
      Western Blot (WB) Assay Dependent

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Flow Cytometry (Flow) See 1 publications below
      Miscellaneous PubMed (MISC) See 1 publications below

      Background/Target Information

      IL-13 is a cytokine involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Flow Cytometry

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Not Applicable Not Cited Variation of T-cell activation in allergic subjects during natural pollen exposure.
      AHC0132 was used in flow cytometry to compare the Th1/Th2 balance in cypress allergic patients with controls       		Koscher V,Milhe F,El Biaze M,Vervloet D,Magnan A Allergy (61:35) 2006

      Miscellaneous PubMed

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human Not Cited Assessment of T lymphocyte cytokine production in induced sputum from asthmatics: a flow cytometry study.
      AHC0132 was used in immunocytochemistry to measure T cell cytokine production in induced sputum.       		Boniface S,Koscher V,Mamessier E,El Biaze M,Dupuy P,Lorec AM,Guillot C,Badier M,Bongrand P,Vervloet D,Magnan A Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (33:1238) 2003

      Bioinformatics

      Protein Aliases:

      ALRH; BHR1; IL-13; Interleukin-13; MGC116786; MGC116788; MGC116789; P600

      Gene Aliases:

      IL-13; IL13; NC30; P600

      UniProt ID:

      (Human) O43644

      Entrez Gene ID:

      (Human) 3596

      Molecular Function:

      cytokine interleukin superfamily signaling molecule

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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