Invitrogen

IL-13 Monoclonal Antibody (JES10-5A2)

Product Image Gallery

IL-13 Antibody in Flow Cytometry (Flow) — Human IL-13 Antibody. Isolated human PBMCs were stimulated and stained with the rat anti-human IL-13 R-PE. Data obtained represent the gated lymphocyte population. The diagram shows stimulated lymphocytes stained with rat anti-human IL-13 R-PE.

Product Details

Tested Applications

Dilution

ELISA (ELISA)

Assay Dependent

Flow Cytometry (Flow)

Assay Dependent

Immunohistochemistry (IHC)

Assay Dependent

Neutralization (Neu)

Assay Dependent

Western Blot (WB)

Assay Dependent

Published Applications

Flow Cytometry (Flow)

See 1 publication below

Miscellaneous PubMed (MISC)

See 1 publication below

Product Specifications

Species Reactivity

Human

Published species

Human

Host / Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

JES10-5A2

Immunogen

Purified recombinant human IL-13

Conjugate

Unconjugated

Form

Liquid

Purification

purified

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C

RRID

AB_2536246

Target Information

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.