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|Tested species reactivity||Human|
|Published species reactivity||Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human IL-8.|
|Storage buffer||PBS, pH 7.5|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 4 publications below|
This product is recommended as a capture antibody in Sandwich ELISA applications.
Interleukin 8 is a pro-inflammatory factor which belongs to the CXC subfamily of chemokinesk, and which are bound by the cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and is a potent angiogenic factor. The expression and secretion of IL-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is present in storage vesicles called Weibel-Palade bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
IL-8 and cathepsin B as melanoma serum biomarkers.
AHC0982 was used in ELISA to study IL8 and Cathepsin B in the prognosis of melanoma mortality.
|Zhang H,Fu T,McGettigan S,Kumar S,Liu S,Speicher D,Schuchter L,Xu X||International journal of molecular sciences (12:1505)||2011|
Biological characterization of lipopolysaccharide from Treponema pectinovorum.
||Kesavalu L,Falk CW,Davis KJ,Steffen MJ,Xu X,Holt SC,Ebersole JL||Infection and immunity (70:211)||2002|
Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence.
||Gujral A,Burton DW,Terkeltaub R,Deftos LJ||Cancer research (61:2282)||2001|
Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts.
||Nixon CS,Steffen MJ,Ebersole JL||Infection and immunity (68:5284)||2000|
NAP-1, GCP1, LECT, MONAP, NAF, LYNAP, NAP1, GCP-1, CXCL8, MDNCF, LUCT
T-cell chemotactic factor, alveolar macrophage chemotactic factor I, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, emoctakin, granulocyte chemotactic protein 1, interleukin-8, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, neutrophil-activating peptide 1, small inducible cytokine subfamily B, member 8, tumor necrosis factor-induced gene 1, Interleukin-8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1