Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
MA1-91096 detects INK4b from human samples.
MA1-91096 has been successfully used in immunofluorescence, immunoprecipitation applications.
The MA1-91096 immunogen is: Puified human recombinant full length p15INK4b protein
The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c andp19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. 5 p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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