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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1146-1173 amino acids from the C-terminal region of human ITGAE|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha polypeptide, integrin alpha-E, integrin alpha-IEL, mucosal lymphocyte 1 antigen; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103, HUMINAE, HML-1 antigen, antigen CD103, human mucosal lymphocyte antigen 1; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; integrin alpha E; integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); mucosal lymphocyte 1 antigen
CD103; HUMINAE; ITGAE