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Invitrogen
L-Plastin Monoclonal Antibody (LPL4A.1)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 18
L-Plastin Antibody (MA5-11921) in ICC/IF
Immunofluorescence analysis of Plastin-L was performed using 70% confluent log phase Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with L-Plastin (LPL4A.1) Mouse Monoclonal Antibody (Product # MA5-11921) at 2 µg/mL in 0.1% BSA and incubated for 3 ... View More
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.jpg?time=20220826?time=20220826 "L-Plastin Antibody (MA5-11921) in ICC/IF")
.jpg?time=20220826?time=20220826 "L-Plastin Antibody (MA5-11921) in WB")
.jpg?time=20220826?time=20220826 "L-Plastin Antibody (MA5-11921) in WB")
Product Details
MA5-11921
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
LPL4A.1
Immunogen
Human recombinant L-plastin protein
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10979969
Product Specific Information
MA5-11921 targets Plastin-L in IF, IP, and WB applications and shows reactivity with Human samples.^M
^M
The MA5-11921 immunogen is human recombinant L-plastin protein.
Target Information
L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosterones in androgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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