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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunoprecipitation (IP) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.86 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808135 |
Immunogen sequence: MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN NNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L; Positive Samples: K-562, HeLa, HepG2, BT-474; Cellular Location: Cytoplasmic side, Lysosome membrane, Peripheral membrane protein
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CMT1C; Estrogen-enhanced transcript protein; FLJ38636; lipopolysaccharide-induced TNF factor; lipopolysaccharide-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; LITAF-like protein; LPS-induced TNF-alpha factor; LPS-induced TNF-alpha factor homolog; mEET; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276; NEDD4 WW domain-binding protein 3; p53-induced gene 7 protein; PIG 7; Small integral membrane protein of lysosome/late endosome; tumor protein p53 inducible protein 7
Gene Aliases: 3222402J11Rik; C85531; LITAF; N4WBP3; PIG7; SIMPLE; TBX1; TP53I7
UniProt ID: (Human) Q99732, (Mouse) Q9JLJ0
Entrez Gene ID: (Human) 9516, (Mouse) 56722
Molecular Function:
scaffold/adaptor protein
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