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Product Details
TA504535
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4E4
Immunogen
Full length human recombinant protein of human LRRC50 produced in HEK293T cell.
Conjugate
Unconjugated
Form
liquid
Concentration
0.76 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Target Information
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dynein (axonemal) assembly factor 1; Dynein axonemal assembly factor 1; dynein, axonemal, assembly factor 1; Leucine-rich repeat-containing protein 50; outer row dynein assembly 7 homolog; testicular tissue protein Li 110
Gene Aliases: CILD13; DNAAF1; LRRC50; ODA7
UniProt ID: (Human) Q8NEP3
Entrez Gene ID: (Human) 123872
Molecular Function:
protein-binding activity modulator
phosphatase modulator
heart looping
cilium movement
regulation of cilium beat frequency
lung development
determination of pancreatic left/right asymmetry
outer dynein arm assembly
inner dynein arm assembly
motile cilium assembly
cilium morphogenesis
epithelial cilium movement involved in determination of left/right asymmetry
left/right pattern formation
axonemal dynein complex assembly
determination of digestive tract left/right asymmetry
determination of liver left/right asymmetry
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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