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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500 | - |
Immunohistochemistry (IHC) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5B1 |
Immunogen |
Recombinant protein within mouse LRRK1 aa 1-164 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% Glycerol, 0.2% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2802557 |
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leucine-rich repeat kinase 1; Leucine-rich repeat serine/threonine-protein kinase 1; LRRK1
Gene Aliases: AW319595; C230002E15Rik; D130026O16Rik; KIAA1790; LRRK1; mKIAA1790; RIPK6; Roco1
UniProt ID: (Human) Q38SD2, (Mouse) Q3UHC2
Entrez Gene ID: (Human) 79705, (Mouse) 233328
Molecular Function:
non-receptor serine/threonine protein kinase
scaffold/adaptor protein
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