|ELISA (ELISA)||Assay Dependent|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Human recombinant Leptin.|
|Storage buffer||PBS, pH 7.5|
|Contains||0.05% sodium azide|
|Storage conditions||4° C|
This product is recommended as a capture antibody in Sandwich ELISA applications.
Leptin is a protein hormone with important effects in regulating body weight, metabolism and reproductive function. The protein is approximately 16 kDa in mass and encoded by the obese (ob) gene. Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body. Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta. Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells. Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD295 antigen; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Obese protein; obese, mouse, homolog of; Obesity factor; obesity protein
Gene Aliases: LEP; LEPD; OB; OBS
UniProt ID: (Human) P41159
Entrez Gene ID: (Human) 3952
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