Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
MA1-518 detects Mist1 from mouse samples. MA1-518 has been successfully used in Western blot. By Western blot, MA1-518 detects a ~29 kDa band representing Mist1. The MA1-518 immunogen is mouse Mist1, N-terminus residues 1-20.
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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