Product References
Retargeted adenoviruses for radiation-guided gene delivery.
Cancer gene therapy
Kaliberov SA,Kaliberova LN,Yan H,Kapoor V,Hallahan DE
MA5-11222 was used in western blot to show the feasibility of adenoviral retargeting of tumor cells using the GRP78-binding peptide
Thu Sep 01 00:00:00 EDT 2016
Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer.
PloS one
Wong CM,Poulin KL,Tong G,Christou C,Kennedy MA,Falls T,Bell JC,Parks RJ
MA511222 was used in western blot to report that adenovirus fusion-associated small transmembrane protein can enhances cancer cell killing in vitro
Wed Aug 03 00:00:00 EDT 2016
Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model.
Cancer gene therapy
Vijayalingam S,Kuppusamy M,Subramanian T,Strebeck FF,West CL,Varvares M,Chinnadurai G
MA5-11222 was used in immunohistochemistry - paraffin section to use a Syrian hamster head and neck cancer model to evaluate apoptogenic adenovirus type 5 oncolytic vectors
Sun Jun 01 00:00:00 EDT 2014
An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.
PloS one
Kim JW,Glasgow JN,Nakayama M,Ak F,Ugai H,Curiel DT
MA5-11222 was used in western blot to study the use of carbohydrate binding domains to target human adenovirus serotype 5 vector-based gene transfer
Mon Jul 15 00:00:00 EDT 2013
Disulfide-bond formation by a single cysteine mutation in adenovirus protein VI impairs capsid release and membrane lysis.
Virology
Moyer CL,Nemerow GR
MA5-11222 was used in western blot to study the role of a cysteine mutation in adenovirus protein VI in impairing capsid release and membrane lysis
Wed Jun 20 00:00:00 EDT 2012
Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.
PloS one
Alberti MO,Roth JC,Ismail M,Tsuruta Y,Abraham E,Pereboeva L,Gerson SL,Curiel DT
MA5-11222 was used in western blot to develop a myeloid cell-binding adenovirus for gene therapy of inflammation
Wed Sep 19 00:00:00 EDT 2012
Functional genetic and biophysical analyses of membrane disruption by human adenovirus.
Journal of virology
Moyer CL,Wiethoff CM,Maier O,Smith JG,Nemerow GR
MA5-11222 was used in western blot to study the genetics and biophysics of membrane disruption by human adenovirus
Tue Mar 01 00:00:00 EST 2011
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
The Prostate
Murakami M,Ugai H,Belousova N,Pereboev A,Dent P,Fisher PB,Everts M,Curiel DT
MA5-11222 was used in western blot to study the use of chimeric adenoviral vectors to mediate gene transfer into prostate cancer cells
Mon Mar 01 00:00:00 EST 2010
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations.
Virology
Murakami M,Ugai H,Wang M,Belousova N,Dent P,Fisher PB,Glasgow JN,Everts M,Curiel DT
MA5-11222 was used in western blot to generate an adenovirus expressing adenovirus 5 and 3 fibre proteins for targeting heterogeneous cell populations
Thu Nov 25 00:00:00 EST 2010
Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.
Molecular therapy : the journal of the American Society of Gene Therapy
Bortolanza S,Bunuales M,Otano I,Gonzalez-Aseguinolaza G,Ortiz-de-Solorzano C,Perez D,Prieto J,Hernandez-Alcoceba R
MA5-11222 was used in western blot to evaluate the therapeutic benefit of an oncolytic adenoviral interleukin-12 construct for pancreatic cancer treatment in an animal model
Wed Apr 01 00:00:00 EDT 2009
INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies.
Cancer gene therapy
Ying B,Toth K,Spencer JF,Meyer J,Tollefson AE,Patra D,Dhar D,Shashkova EV,Kuppuswamy M,Doronin K,Thomas MA,Zumstein LA,Wold WS,Lichtenstein DL
MA5-11222 was used in immunohistochemistry to compare the biodistribution of an oncolytic adenovirus in Syrian hamsters in which it replicates and mice in which it does not replicate
Sat Aug 01 00:00:00 EDT 2009
Insufficient accumulation of viral late mRNAs restricts the replicative cycle of human adenovirus type 37 in A549 cells.
Archives of virology
Adachi K,Mitani K
MA5-11222 was used in western blot to study the replicative cycle of the poorly growing human adenovirus type 37 serotype
Fri Nov 13 00:00:00 EST 2009
Autophagy pathways in glioblastoma.
Methods in enzymology
Jiang H,White EJ,Conrad C,Gomez-Manzano C,Fueyo J
MA5-11222 was used in immunohistochemistry to discus the role and therapeutic potential of autophagy pathways in glioblastoma
Thu Apr 02 00:00:00 EDT 2009
A strategy for adenovirus vector targeting with a secreted single chain antibody.
PloS one
Glasgow JN,Mikheeva G,Krasnykh V,Curiel DT
MA5-11222 was used in western blot to develop targeted adenovirus vectors utilizing a secreted single-chain antibody sequence
Mon Dec 21 00:00:00 EST 2009
A ligand-pseudoreceptor system based on de novo designed peptides for the generation of adenoviral vectors with altered tropism.
The journal of gene medicine
Zeng Y,Pinard M,Jaime J,Bourget L,Uyen Le P,O'Connor-McCourt MD,Gilbert R,Massie B
MA5-11222 was used in immunocytochemistry and western blot to develop a new system for producing adenoviruses ablated of natural tropism
Tue Apr 01 00:00:00 EDT 2008
Improved retinal transduction in vivo and photoreceptor-specific transgene expression using adenovirus vectors with modified penton base.
Molecular therapy : the journal of the American Society of Gene Therapy
Cashman SM,McCullough L,Kumar-Singh R
MA5-11222 was used in western blot to develop adenoviral vectors with improved retinal transduction in vivo and photoreceptor-specific transgene expression
Sat Sep 01 00:00:00 EDT 2007
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death.
Journal of the National Cancer Institute
Jiang H,Gomez-Manzano C,Aoki H,Alonso MM,Kondo S,McCormick F,Xu J,Kondo Y,Bekele BN,Colman H,Lang FF,Fueyo J
MA5-11222 was used in immunohistochemistry to study the therapeutic potential of an oncolytic adenovirus in brain tumor stem cells
Wed Sep 19 00:00:00 EDT 2007
Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery.
Journal of virology
Li J,Lad S,Yang G,Luo Y,Iacobelli-Martinez M,Primus FJ,Reisfeld RA,Li E
MA5-11222 was used in western blot to study a novel trimerization element in the adenovirus fiber shaft with potential for targeted gene delivery
Fri Dec 01 00:00:00 EST 2006
CD46-utilizing adenoviruses inhibit C/EBPbeta-dependent expression of proinflammatory cytokines.
Journal of virology
Iacobelli-Martinez M,Nepomuceno RR,Connolly J,Nemerow GR
MA5-11222 was used in western blot to study the mechanism by which CD46-utilizing adenoviruses inhibit inflammatory cytokine expression
Thu Sep 01 00:00:00 EDT 2005
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy.
Gene therapy
Stoff-Khalili MA,Rivera AA,Glasgow JN,Le LP,Stoff A,Everts M,Tsuruta Y,Kawakami Y,Bauerschmitz GJ,Mathis JM,Pereboeva L,Seigal GP,Dall P,Curiel DT
MA5-11222 was used in immunohistochemistry to study the expanded tropism of a novel human adenoviral vector containing a chimeric fibre and the significance for cancer gene therapy
Thu Dec 01 00:00:00 EST 2005
Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression.
Gene therapy
Pipiya T,Sauthoff H,Huang YQ,Chang B,Cheng J,Heitner S,Chen S,Rom WN,Hay JG
MA5-11222 was used in western blot to study the role of hypoxia in downregulating viral protein expression in cancer cells
Wed Jun 01 00:00:00 EDT 2005
Replication-dependent transgene expression from a conditionally replicating adenovirus via alternative splicing to a heterologous splice-acceptor site.
The journal of gene medicine
Carette JE,Graat HC,Schagen FH,Abou El Hassan MA,Gerritsen WR,van Beusechem VW
MA5-11222 was used in western blot to develop oncolytic adenoviruses for cancer therapy
Mon Aug 01 00:00:00 EDT 2005
Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors.
Virus research
Pereboeva L,Komarova S,Mahasreshti PJ,Curiel DT
MA5-11222 was used in western blot to evaluate fiber-mosaic adenovirus as a novel adenoviral vector
Wed Sep 15 00:00:00 EDT 2004
Robust infectivity and replication of Delta-24 adenovirus induce cell death in human medulloblastoma.
Cancer gene therapy
Stolarek R,Gomez-Manzano C,Jiang H,Suttle G,Lemoine MG,Fueyo J
MA5-11222 was used in western blot to study the ability of a mutant Delta-24 adenovirus to induce cell death in human medulloblastoma
Mon Nov 01 00:00:00 EST 2004
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.
Virology
Glasgow JN,Kremer EJ,Hemminki A,Siegal GP,Douglas JT,Curiel DT
MA5-11222 was used in western blot to develop a novel chimeric adenovirus vector with broader cell infectivity
Sun Jun 20 00:00:00 EDT 2004
Telomerase-dependent oncolytic adenovirus for cancer treatment.
Gene therapy
Huang TG,Savontaus MJ,Shinozaki K,Sauter BV,Woo SL
MA5-11222 was used in immunohistochemistry to develop a telomerase-dependent oncolytic adenovirus for cancer treatment
Fri Aug 01 00:00:00 EDT 2003
Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency.
Cancer research
van Beusechem VW,van den Doel PB,Grill J,Pinedo HM,Gerritsen WR
MA5-11222 was used in western blot to study the oncolytic potency and therapeutic potential of conditionally replicative adenovirus expressing p53
Fri Nov 01 00:00:00 EST 2002