Product References
Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme.
eLife
Jacquemin G,Wurmser A,Huyghe M,Sun W,Homayed Z,Merle C,Perkins M,Qasrawi F,Richon S,Dingli F,Arras G,Loew D,Vignjevic D,Pannequin J,Fre S
MA5-13377 was used in Neutralization experiments to reveal the THBS1-YAP axis as the mechanistic link mediating paracrine interactions between epithelial cells in intestinal tumours.
Wed May 11 00:00:00 EDT 2022
Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages.
Journal of leukocyte biology
Ernens I,Bousquenaud M,Lenoir B,Devaux Y,Wagner DR
MA5-13377 was used in Functional assay, Inhibition Assays to determine whether Ado modulates TSP-1 expression and the implication on angiogenesis.
Thu Jan 01 00:00:00 EST 2015
Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages.
Journal of leukocyte biology
Ernens I,Bousquenaud M,Lenoir B,Devaux Y,Wagner DR
MA5-13377 was used in Functional assay, Inhibition Assays to determine whether Ado modulates TSP-1 expression and the implication on angiogenesis.
Thu Jan 01 00:00:00 EST 2015
Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages.
Journal of leukocyte biology
Ernens I,Bousquenaud M,Lenoir B,Devaux Y,Wagner DR
MA5-13377 was used in Functional assay, Inhibition Assays to determine whether Ado modulates TSP-1 expression and the implication on angiogenesis.
Thu Jan 01 00:00:00 EST 2015
Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages.
Journal of leukocyte biology
Ernens I,Bousquenaud M,Lenoir B,Devaux Y,Wagner DR
MA5-13377 was used in Functional assay, Inhibition Assays to determine whether Ado modulates TSP-1 expression and the implication on angiogenesis.
Thu Jan 01 00:00:00 EST 2015
Mutations in FKBP14 cause a variant of Ehlers-Danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss.
American journal of human genetics
Baumann M,Giunta C,Krabichler B,Rüschendorf F,Zoppi N,Colombi M,Bittner RE,Quijano-Roy S,Muntoni F,Cirak S,Schreiber G,Zou Y,Hu Y,Romero NB,Carlier RY,Amberger A,Deutschmann A,Straub V,Rohrbach M,Steinmann B,Rostásy K,Karall D,Bönnemann CG,Zschocke J,Fauth C
MA5-13377 was used in immunocytochemistry to study the role of a FKBP14 mutation in the pathogenesis of a variant of Ehlers-Danlos syndrome
Fri Feb 10 00:00:00 EST 2012
Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes.
Journal of cellular biochemistry
Chen JK,Zhan YJ,Yang CS,Tzeng SF
MA5-13377 was used in western blot to investigate the effect of oxidative stress on thrombospondin 1 expression in astrocytes
Sat Jan 01 00:00:00 EST 2011
Role of thrombospondin 1 in macrophage inflammation in dysferlin myopathy.
Journal of neuropathology and experimental neurology
De Luna N,Gallardo E,Sonnet C,Chazaud B,Dominguez-Perles R,Suarez-Calvet X,Gherardi RK,Illa I
MA5-13377 was used in blocking or activating experiment to investigate the influence of TSP-1 on macrophage inflammation in dysferlin myopathy
Tue Jun 01 00:00:00 EDT 2010
Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1.
Cancer research
Goel HL,Moro L,Murphy-Ullrich JE,Hsieh CC,Wu CL,Jiang Z,Languino LR
MA5-13377 was used in blocking/activating experiment to study the effect of beta 1 integrin on the expression of extracellular matrix protein thrombospondin 1
Wed Jul 01 00:00:00 EDT 2009
Estrogen regulation of thrombospondin-1 in human breast cancer cells.
International journal of cancer
Hyder SM,Liang Y,Wu J
MA5-13377 was used in blocking or activating experiment to study the regulation of thrombospondin-1 expression by estrogen in human breast cancer cells
Tue Sep 01 00:00:00 EDT 2009
Regulation of thrombospondin-1 by natural and synthetic progestins in human breast cancer cells.
Endocrine-related cancer
Hyder SM,Liang Y,Wu J,Welbern V
MA5-13377 was used in blocking or activating experiment to study the regulation of thrombospondin-1 expression by natural and synthetic progestins in human breast cancer cells
Tue Sep 01 00:00:00 EDT 2009
Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation.
Journal of neurochemistry
Moore NH,Costa LG,Shaffer SA,Goodlett DR,Guizzetti M
MA5-13377 was used in western blot to identify astrocyte-released proteins involved in neuronal maturation
Sun Feb 01 00:00:00 EST 2009
Angiostatic factors normally restrict islet endothelial cell proliferation and migration: implications for islet transplantation.
Transplant international : official journal of the European Society for Organ Transplantation
Johansson A,Olerud J,Johansson M,Carlsson PO
MA5-13377 was used in blocking or activating experiment to develop an in vitro model to study factors affecting the migration and proliferation of isolated liver and islet endothelium
Tue Dec 01 00:00:00 EST 2009
Meteorin regulates angiogenesis at the gliovascular interface.
Glia
Park JA,Lee HS,Ko KJ,Park SY,Kim JH,Choe G,Kweon HS,Song HS,Ahn JC,Yu YS,Kim KW
MA5-13377 was used in blocking or activating experiment to investigate the role of meteorin in angiogenesis at the gliovascular interface
Fri Feb 01 00:00:00 EST 2008
Collagen-binding domains of gelatinase A and thrombospondin-derived peptides impede endocytic clearance of active gelatinase A and promote HT1080 fibrosarcoma cell invasion.
Life sciences
Robinet A,Emonard H,Banyai L,Laronze JY,Patthy L,Hornebeck W,Bellon G
MA5-13377 was used in western blot to study the mechanism by which collagen-binding domains of gelatinase A and thrombospondin promote fibrosarcoma cell invasion
Wed Feb 13 00:00:00 EST 2008
CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A.
Journal of cellular biochemistry
Kang JH,Kim MJ,Chang SY,Sim SS,Kim MS,Jo YH
MA5-13377 was used in western blot to investigate the role of the CCAAT box in the induction of human thrombospondin-1 gene by trichostatin A
Tue Jul 01 00:00:00 EDT 2008
A new insight into phagocytosis of apoptotic cells: proteolytic enzymes divert the recognition and clearance of polymorphonuclear leukocytes by macrophages.
Cell death and differentiation
Guzik K,Bzowska M,Smagur J,Krupa O,Sieprawska M,Travis J,Potempa J
MA5-13377 was used in blocking or activating experiment to study the in vivo clearance of apoptotic cells by macrophages
Mon Jan 01 00:00:00 EST 2007
PPARalpha deficiency in inflammatory cells suppresses tumor growth.
PloS one
Kaipainen A,Kieran MW,Huang S,Butterfield C,Bielenberg D,Mostoslavsky G,Mulligan R,Folkman J,Panigrahy D
MA5-13377 was used in blocking or activating experiment to study the effect of PPARalpha deficiency in inflammatory cells on tumor growth
Wed Feb 28 00:00:00 EST 2007
A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype.
Journal of the National Cancer Institute
Naumov GN,Bender E,Zurakowski D,Kang SY,Sampson D,Flynn E,Watnick RS,Straume O,Akslen LA,Folkman J,Almog N
MA5-13377 was used in western blot to study the angiogenesis during human tumor progression
Wed Mar 01 00:00:00 EST 2006
NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype.
Oncogene
Hasina R,Pontier AL,Fekete MJ,Martin LE,Qi XM,Brigaudeau C,Pramanik R,Cline EI,Coignet LJ,Lingen MW
MA5-13377 was used in blocking or activating experiment to study the role of NOL7 in cervical cancer
Thu Jan 26 00:00:00 EST 2006
LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity: Role of extracellular proteases plasmin and elastase.
Journal of cellular biochemistry
Gomez-Duran A,Mulero-Navarro S,Chang X,Fernandez-Salguero PM
MA5-13377 was used in blocking or activating experiment to study the mechanisms by which LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity
Wed Feb 01 00:00:00 EST 2006
Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.
Nature medicine
Kermorvant-Duchemin E,Sennlaub F,Sirinyan M,Brault S,Andelfinger G,Kooli A,Germain S,Ong H,d'Orleans-Juste P,Gobeil F,Zhu T,Boisvert C,Hardy P,Jain K,Falck JR,Balazy M,Chemtob S
MA5-13377 was used in immunohistochemistry to study thrombospondin-1-dependent microvascular degeneration induced by transarachidonic acids during nitrative stress.
Thu Dec 01 00:00:00 EST 2005
Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch.
The American journal of pathology
Cambier S,Gline S,Mu D,Collins R,Araya J,Dolganov G,Einheber S,Boudreau N,Nishimura SL
MA5-13377 was used in western blot to study the molecular mechanisms underlying astrocytic-endothelial paracrine signaling
Wed Jun 01 00:00:00 EDT 2005
Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism.
The Journal of biological chemistry
Emonard H,Bellon G,Troeberg L,Berton A,Robinet A,Henriet P,Marbaix E,Kirkegaard K,Patthy L,Eeckhout Y,Nagase H,Hornebeck W,Courtoy PJ
MA5-13377 was used in blocking or activating experiment to investigate the mechanism of endocytic clearance mediated by low density lipoprotein receptor-related protein
Fri Dec 24 00:00:00 EST 2004
Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts.
Cancer research
Rofstad EK,Henriksen K,Galappathi K,Mathiesen B
MA5-13377 was used in immunohistochemistry to study the effect of thrombospondin-1 treatment on the response to radiation therapy in human melanoma xenografts
Tue Jul 15 00:00:00 EDT 2003
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy.
Proceedings of the National Academy of Sciences of the United States of America
Bocci G,Francia G,Man S,Lawler J,Kerbel RS
MA5-13377 was used in blocking or activating experiment to study the contribution of thrombospondin-1 to the antiangiogenic effects of low-dose metronomic chemotherapy
Tue Oct 28 00:00:00 EST 2003
Thrombospondin-1 promotes fibroblast-mediated collagen gel contraction caused by activation of latent transforming growth factor beta-1.
Journal of dermatological science
Sakai K,Sumi Y,Muramatsu H,Hata K,Muramatsu T,Ueda M
MA5-13377 was used in blocking or activating experiment to study the role of thrombospondin-1 in fibroblast-mediated collagen gel contraction
Tue Apr 01 00:00:00 EST 2003
Thrombospondin 2 regulates cell proliferation induced by Rac1 redox-dependent signaling.
Molecular and cellular biology
Lopes N,Gregg D,Vasudevan S,Hassanain H,Goldschmidt-Clermont P,Kovacic H
MA5-13377 was used in immunocytochemistry to investigate the relationship between thrombospondin 2 and Rac1
Fri Aug 01 00:00:00 EDT 2003
Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS.
Neuroscience
Rhodes KE,Moon LD,Fawcett JW
MA5-13377 was used in immunohistochemistry to study the effect of inhibiting cell proliferation on glial scar formation and CNS axon regeneration
Tue Sep 30 00:00:00 EDT 2003
Effects of cerivastatin on human arterial smooth muscle cell growth and extracellular matrix expression at varying glucose and low-density lipoprotein levels.
Journal of cardiovascular pharmacology
Siegel-Axel DI,Runge H,Seipel L,Riessen R
MA5-13377 was used in immunocytochemistry to study the effects of cerivastatin on human arterial smooth muscle cell growth and extracellular matrix at different concentrations of glucose and LDL
Sat Mar 01 00:00:00 EST 2003
Adhesion of normal erythrocytes at depressed venous shear rates to activated neutrophils, activated platelets, and fibrin polymerized from plasma.
Blood
Goel MS,Diamond SL
MA5-13377 was used in blocking or activating experiment to investigate the adhesion of erythrocytes during deep vein thrombosis
Fri Nov 15 00:00:00 EST 2002
Thrombospondin-1-mediated metastasis suppression by the primary tumor in human melanoma xenografts.
The Journal of investigative dermatology
Rofstad EK,Graff BA
MA5-13377 was used in blocking or activating experiment to study the role of thrombospondin-1 in the supression of metastasis by the primary tumor in a human melanoma xenograft model
Thu Nov 01 00:00:00 EST 2001
Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin.
Biochimica et biophysica acta
Gupta K,Gupta P,Solovey A,Hebbel RP
MA5-13377 was used in blocking or activating experiment to study the mechanism by which thrombospondin mediates the adhesion of sickle erythrocytes to endothelium
Wed Jan 06 00:00:00 EST 1999