For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
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Protein Aliases: ACE; ACE1; angiotensin 1 converting enzyme 1; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); Angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; angiotensin-converting enzyme-like; carboxycathepsin; CD143; CD143 antigen; DCP; DCP1; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); Dipeptidyl carboxypeptidase I; Kininase II; MGC26566; MVCD3; peptidase P; testicular ECA
Gene Aliases: ACE; ACE1; CD143; DCP; DCP1; I79_009670; ICH; MVCD3; StsRR92