Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: LLNRIRTWQK THQGENNGLA NSIRDSLNEY EAKLSDLRAR LQEAAAQAKQ ANGLNQENER ALGAIQRQVK EINSLQSDFT KYLTTADSSL LQTNIALQLM EKSQKEYE
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 71%.
Binds to an epitope located within the peptide sequence EINSLQSDFT as determined by overlapping synthetic peptides.
Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BM600 150kD subunit; E170; Epiligrin; Epiligrin 170 kDa subunit; epiligrin alpha 3 subunit; Epiligrin subunit alpha; kalinin 165kD subunit; Kalinin subunit alpha; LAM3, alpha-3 subunit; laminin 5, alpha-3 subunit; laminin A3; Laminin subunit alpha-3; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin); Laminin-5; laminin-5 alpha 3 chain; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; nicein 150kD subunit; Nicein subunit alpha
Gene Aliases: BM600; E170; LAMA3; LAMNA; LOCS
UniProt ID: (Human) Q16787
Entrez Gene ID: (Human) 3909
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