TMOD1 gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E tropomodulin 1; E-Tmod; E-Tropomodulin; Erythrocyte tropomodulin; Tropomodulin-1
Gene Aliases: D9S57E; E-Tmod; ETMOD; TMOD; TMOD1