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Product Details
MA5-29439
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
Class
Monoclonal
Type
Antibody
Clone
06
Immunogen
Recombinant Human KNG1/Kininogen 1 Protein (Gln19-Ser644)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785301
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human KNG1/Kininogen 1.
Target Information
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-thiol proteinase inhibitor; bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; Kininogen-1; Williams-Fitzgerald-Flaujeac factor
Gene Aliases: BDK; BK; KNG; KNG1
UniProt ID: (Human) P01042
Entrez Gene ID: (Human) 3827
platelet degranulation
smooth muscle contraction
inflammatory response
negative regulation of cell adhesion
positive regulation of cytosolic calcium ion concentration
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
negative regulation of blood coagulation
positive regulation of urine volume
positive regulation of renal sodium excretion
vasodilation
positive regulation of apoptotic process
negative regulation of proteolysis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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