Product References
Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.
Nature communications
Lee H,Noh H,Mun J,Gu C,Sever S,Park S
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA5-12998) in Immunofluorescence
Tue Sep 13 00:00:00 EDT 2016
Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.
Nature communications
Lee H,Noh H,Mun J,Gu C,Sever S,Park S
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA5-12998) in Immunofluorescence
Tue Sep 13 00:00:00 EDT 2016
Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.
Nature communications
Lee H,Noh H,Mun J,Gu C,Sever S,Park S
Published figure using ErbB2 (HER-2) monoclonal antibody (Product # MA5-12998) in Immunofluorescence
Tue Sep 13 00:00:00 EDT 2016
Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.
Breast cancer research : BCR
DeFazio-Eli L,Strommen K,Dao-Pick T,Parry G,Goodman L,Winslow J
MA5-12998 was used in immunoprecipitation to investigate the state of HER1-HER2 interaction and modification in cell lines and tumors
Fri Apr 15 00:00:00 EDT 2011
Silica-gold nanoshells as potential intraoperative molecular probes for HER2-overexpression in ex vivo breast tissue using near-infrared reflectance confocal microscopy.
Breast cancer research and treatment
Bickford LR,Agollah G,Drezek R,Yu TK
MA5-12998 was used in immunocytochemistry to study silica-gold nanoshells as potential probes for HER2-overexpression in ex vivo breast tissue
Thu Apr 01 00:00:00 EDT 2010
Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens.
Pathology research international
Larson JS,Goodman LJ,Tan Y,Defazio-Eli L,Paquet AC,Cook JW,Rivera A,Frankson K,Bose J,Chen L,Cheung J,Shi Y,Irwin S,Kiss LD,Huang W,Utter S,Sherwood T,Bates M,Weidler J,Parry G,Winslow J,Petropoulos CJ,Whitcomb JM
MA5-12998 was used in flow cytometry to validate a method for the measurement of HER2 total protein and HER2 homodimers in FFPE breast cancer tumor specimens
Mon Jun 28 00:00:00 EDT 2010
Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.
Cancer research
Gilmer TM,Cable L,Alligood K,Rusnak D,Spehar G,Gallagher KT,Woldu E,Carter HL,Truesdale AT,Shewchuk L,Wood ER
MA5-12998 was used in immunoprecipitation to investigate the effect of lapatinib on cell proliferation regulated by EGFR/HER2
Tue Jan 15 00:00:00 EST 2008
Enhanced multi-spectral imaging of live breast cancer cells using immunotargeted gold nanoshells and two-photon excitation microscopy.
Nanotechnology
Bickford L,Sun J,Fu K,Lewinski N,Nammalvar V,Chang J,Drezek R
MA5-12998 was used in immunocytochemistry to develop a method for multi-spectral imaging of live breast cancer cells using immunotargeted gold nanoshells
Wed Aug 06 00:00:00 EDT 2008
Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles.
Molecular cancer therapeutics
Hegde PS,Rusnak D,Bertiaux M,Alligood K,Strum J,Gagnon R,Gilmer TM
MA5-12998 was used in immunocytochemistry to examine the mechanism for the lapatinib sensitivity in breast cancer cell lines
Tue May 01 00:00:00 EDT 2007
Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients.
International immunology
Oldford SA,Robb JD,Codner D,Gadag V,Watson PH,Drover S
MA5-12998 was used in immunohistochemistry to study the predictive value of tumor cell expression of HLA-DM in breast carcinoma patients
Wed Nov 01 00:00:00 EST 2006
Immunonanoshells for targeted photothermal ablation of tumor cells.
International journal of nanomedicine
Lowery AR,Gobin AM,Day ES,Halas NJ,West JL
MA5-12998 was used in immunocytochemistry to study the use of immunonanoshells for targeted photothermal ablation of tumor cells
Tue Sep 18 00:00:00 EDT 2007
Isolation of scFvs to in vitro produced extracellular domains of EGFR family members.
Cancer biotherapy & radiopharmaceuticals
Horak E,Heitner T,Robinson MK,Simmons HH,Garrison J,Russeva M,Furmanova P,Lou J,Zhou Y,Yuan QA,Weiner LM,Adams GP,Marks JD
MA5-12998 was used in western blot to develop and characterize specific antibodies targeting EGFR family
Thu Dec 01 00:00:00 EST 2005
Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2.
Cancer cell
Wang SC,Lien HC,Xia W,Chen IF,Lo HW,Wang Z,Ali-Seyed M,Lee DF,Bartholomeusz G,Ou-Yang F,Giri DK,Hung MC
MA5-12998 was used in EMSA to investigate the influence of ErbB-2 on COX-2 expression and its mechanism
Wed Sep 01 00:00:00 EDT 2004
C-erbB2 oncoprotein and its soluble ectodomain: a new potential tumor marker for prognosis early detection and monitoring patients undergoing Herceptin treatment.
Clinica chimica acta; international journal of clinical chemistry
Wu JT
MA5-12998 was used in ELISA to investigate the prognostic value of C-erbB2 oncoprotein in Herceptin treatment
Thu Aug 01 00:00:00 EDT 2002