Product References
Changes in the cellular localization of estrogen receptor alpha in the growing and regressing ovaries of Gallus domesticus during development.
Biochemical and biophysical research communications
González-Morán MG
MA5-13062 was used in immunohistochemistry to study ER-alpha localization in the growing and regressing ovaries of developing Gallus domesticus chicks
Fri Apr 25 00:00:00 EDT 2014
Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level.
Cancer research
Miranda TB,Voss TC,Sung MH,Baek S,John S,Hawkins M,Grøntved L,Schiltz RL,Hager GL
MA5-13062 was used in ChIP assay to study the role of chromatin reorganization in the genomic level interactions between the estrogen and glucocorticoid receptors
Thu Aug 15 00:00:00 EDT 2013
Early histone modifications in the ventromedial hypothalamus and preoptic area following oestradiol administration.
Journal of neuroendocrinology
Gagnidze K,Weil ZM,Faustino LC,Schaafsma SM,Pfaff DW
MA5-13062 was used in ChIP assay to study the effects of estradiol treatment on histones in he ventromedial hypothalamus and the preoptic area
Tue Oct 01 00:00:00 EDT 2013
Characterization of estrogen response element binding proteins as biomarkers of breast cancer behavior.
Clinical biochemistry
Kruer TL,Cummins TD,Powell DW,Wittliff JL
MA5-13062 was used in EMSA to study the prognostic value of estrogen resonse element binding proteins in breast cancer
Fri Nov 01 00:00:00 EDT 2013
Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing.
BMC medical genomics
Bhat-Nakshatri P,Song EK,Collins NR,Uversky VN,Dunker AK,O'Malley BW,Geistlinger TR,Carroll JS,Brown M,Nakshatri H
MA5-13062 was used in ChIP assay to study alternative splicing induced by estradiol and the role of ER-Akt interactions
Tue Jun 11 00:00:00 EDT 2013
Estrogen receptor α L543A,L544A mutation changes antagonists to agonists, correlating with the ligand binding domain dimerization associated with DNA binding activity.
The Journal of biological chemistry
Arao Y,Hamilton KJ,Coons LA,Korach KS
MA5-13062 was used in western blot to study the molecular mechanism by which ER-alpha mutations can convert antagonist ligands to agonists
Fri Jul 19 00:00:00 EDT 2013
MLL-ENL inhibits polycomb repressive complex 1 to achieve efficient transformation of hematopoietic cells.
Cell reports
Maethner E,Garcia-Cuellar MP,Breitinger C,Takacova S,Divoky V,Hess JL,Slany RK
MA5-13062 was used in ChIP assay to study the transformation of hematopoietic cells and the role of PRC1 inhibition by MLL-ENL
Thu May 30 00:00:00 EDT 2013
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
Genome research
He HH,Meyer CA,Chen MW,Jordan VC,Brown M,Liu XS
MA5-13062 was used in ChIP assay to study DNase I hypersensitivity and chromatin dynamics
Fri Jun 01 00:00:00 EDT 2012
Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence.
International journal of cancer
Tuttle R,Miller KR,Maiorano JN,Termuhlen PM,Gao Y,Berberich SJ
MA5-13062 was used in western blot to study the role of the YPEL3 senescence gene in the sensitivity of ER-positive mammary tumor cells to senescence induced by tamoxifen
Tue May 15 00:00:00 EDT 2012
Localization of estrogen receptor in the central lymphoid organs of chickens during the late stage of embryogenesis.
Bioscience, biotechnology, and biochemistry
Katayama M,Fukuda T,Narabara K,Abe A,Kondo Y
MA5-13062 was used in immunohistochemistry to study estrogen receptor expression in developing chick embryo central lymphoid tissue and the significance for immune function
Fri May 17 00:00:00 EDT 2013
Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb.
Nucleic acids research
Zhao L,Glazov EA,Pattabiraman DR,Al-Owaidi F,Zhang P,Brown MA,Leo PJ,Gonda TJ
MA5-13062 was used in ChIP assay to study the mechanisms by which the Myb transcription factor controls normal hematopoiesis and how it contributes to leukemogenesis
Wed Jun 01 00:00:00 EDT 2011
GATA4 regulates estrogen receptor-alpha-mediated osteoblast transcription.
Molecular endocrinology (Baltimore, Md.)
Miranda-Carboni GA,Guemes M,Bailey S,Anaya E,Corselli M,Peault B,Krum SA
MA5-13062 was used in immunoprecipitation to study the role of GATA4 in regulating estrogen receptor-alpha-mediated osteoblast transcription
Fri Jul 01 00:00:00 EDT 2011
Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications.
The American journal of pathology
Badve S,Collins NR,Bhat-Nakshatri P,Turbin D,Leung S,Thorat M,Dunn SE,Geistlinger TR,Carroll JS,Brown M,Bose S,Teitell MA,Nakshatri H
MA5-13062 was used in ChIP assay to investigate the subcellular distribution of phospho-AKT in estrogen receptor alpha-positive breast cancers
Sat May 01 00:00:00 EDT 2010
The tri-nucleotide spacer sequence between estrogen response element half-sites is conserved and modulates ERalpha-mediated transcriptional responses.
The Journal of steroid biochemistry and molecular biology
Shu FJ,Sidell N,Yang D,Kallen CB
MA5-13062 was used in EMSA to study the role of the tri-nucleotide spacer sequence in the estrogen response element in regulating ER alpha-mediated transcriptional responses
Tue Jun 01 00:00:00 EDT 2010
Coactivator function defines the active estrogen receptor alpha cistrome.
Molecular and cellular biology
Lupien M,Eeckhoute J,Meyer CA,Krum SA,Rhodes DR,Liu XS,Brown M
MA5-13062 was used in ChIP assay to study the activation of the estrogen receptor alpha cistrome in breast cancer cells
Mon Jun 01 00:00:00 EDT 2009
Differential actions of estrogen and SERMs in regulation of the actin cytoskeleton of endometrial cells.
Molecular human reproduction
Flamini MI,Sanchez AM,Goglia L,Tosi V,Genazzani AR,Simoncini T
MA5-13062 was used in western blot to study the differential effects of estrogen and selective estrogen receptor modulators on the actin cytoskeleton of human endometrial cells
Thu Oct 01 00:00:00 EDT 2009
Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells.
PloS one
Salama SA,Kamel MW,Botting S,Salih SM,Borahay MA,Hamed AA,Kilic GS,Saeed M,Williams MY,Diaz-Arrastia CR
MA5-13062 was used in immunocytochemistry to investigate the influence of catechol-o-methyltransferase and 2-methoxyestradiol on cytoskeleton structure and steroid receptor signaling
Wed Oct 07 00:00:00 EDT 2009
EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.
The Journal of biological chemistry
Tallack MR,Keys JR,Humbert PO,Perkins AC
MA5-13062 was used in ChIP assay to study the mechanism by which EKLF/KLF1 controls cell cycle entry
Fri Jul 31 00:00:00 EDT 2009
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.
The EMBO journal
Krum SA,Miranda-Carboni GA,Hauschka PV,Carroll JS,Lane TF,Freedman LP,Brown M
MA5-13062 was used in immunocytochemistry to study a mechanism by which estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival
Wed Feb 06 00:00:00 EST 2008
Interaction of MLL amino terminal sequences with menin is required for transformation.
Cancer research
Caslini C,Yang Z,El-Osta M,Milne TA,Slany RK,Hess JL
MA5-13062 was used in ChIP assay to study the role of MLL N-terminal interactions with the menin tumor suppressor in the transformation of hematopoietic progenitors
Wed Aug 01 00:00:00 EDT 2007
Erythroid Kruppel-like factor regulates the G1 cyclin dependent kinase inhibitor p18INK4c.
Journal of molecular biology
Tallack MR,Keys JR,Perkins AC
MA5-13062 was used in ChIP assay to study the role of erythroid Kruppel-like factor in regulating the G1 cyclin dependent kinase inhibitor p18INK4c
Fri Jun 01 00:00:00 EDT 2007
Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase/Akt pathway.
Endocrinology
Kazi AA,Koos RD
MA5-13062 was used in ChIP assay and western blot to study the role of the PI3Kinase/Akt pathway in the estrogen-induced activation of HIF-1alpha and VEGF expression and edema in the uterus
Tue May 01 00:00:00 EDT 2007
Physiologically high concentrations of 17beta-estradiol enhance NF-kappaB activity in human T cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Hirano S,Furutama D,Hanafusa T
MA5-13062 was used in ChIP assay, immunoprecipitation, and western blot to study the effects of physiologically high concentrations of 17beta-estradiol on NFkB activity in human T cells
Sun Apr 01 00:00:00 EDT 2007
Genome-wide analysis of estrogen receptor binding sites.
Nature genetics
Carroll JS,Meyer CA,Song J,Li W,Geistlinger TR,Eeckhoute J,Brodsky AS,Keeton EK,Fertuck KC,Hall GF,Wang Q,Bekiranov S,Sementchenko V,Fox EA,Silver PA,Gingeras TR,Liu XS,Brown M
MA5-13062 was used in ChIP assay to perform a genome-wide analysis of estrogen receptor binding sites
Wed Nov 01 00:00:00 EST 2006
Estrogen receptor protein interaction with phosphatidylinositol 3-kinase leads to activation of phosphorylated Akt and extracellular signal-regulated kinase 1/2 in the same population of cortical neurons: a unified mechanism of estrogen action.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Mannella P,Brinton RD
MA5-13062 was used in immunoprecipitation to study the role of phosphatidylinositol 3-kinase in estrogen receptor signaling pathways in cortical neurons
Wed Sep 13 00:00:00 EDT 2006
Identification of estrogen receptor ligands leading to activation of non-genomic signaling pathways while exhibiting only weak transcriptional activity.
The Journal of steroid biochemistry and molecular biology
Wessler S,Otto C,Wilck N,Stangl V,Fritzemeier KH
MA5-13062 was used in immunoprecipitation to study estrogen receptor ligands that activate non-genomic signaling pathways
Sun Jan 01 00:00:00 EST 2006
Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat.
Biochemical and biophysical research communications
Shirai M,Yamanaka M,Shiina H,Igawa M,Kawakami T,Ishii N,Lue TF,Fujime M,Dahiya R
MA5-13062 was used in immunohistochemistry to study the mechanism by which VEGF restores erectile function in the diabetic rat
Fri Mar 17 00:00:00 EST 2006
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.
Cell
Carroll JS,Liu XS,Brodsky AS,Li W,Meyer CA,Szary AJ,Eeckhoute J,Shao W,Hestermann EV,Geistlinger TR,Fox EA,Silver PA,Brown M
MA5-13062 was used in ChIP assay to study the role of the forkhead protein FoxA1 estrogen receptor binding to estrogen-induced genes
Fri Jul 15 00:00:00 EDT 2005
Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications.
Cancer research
Milne TA,Martin ME,Brock HW,Slany RK,Hess JL
MA5-13062 was used in ChIP assay to study the mechanisms by which leukemogenic MLL proteins induce multiple modifications of histones
Thu Dec 15 00:00:00 EST 2005
Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.
Molecular endocrinology (Baltimore, Md.)
Sentis S,Le Romancer M,Bianchin C,Rostan MC,Corbo L
MA5-13062 was used in immunoprecipitation to study the regulation of estrogen receptor alpha transcriptional activity by sumoylation of its hinge region
Tue Nov 01 00:00:00 EST 2005
An estrogen receptor-alpha/p300 complex activates the BRCA-1 promoter at an AP-1 site that binds Jun/Fos transcription factors: repressive effects of p53 on BRCA-1 transcription.
Neoplasia (New York, N.Y.)
Jeffy BD,Hockings JK,Kemp MQ,Morgan SS,Hager JA,Beliakoff J,Whitesell LJ,Bowden GT,Romagnolo DF
MA5-13062 was used in ChIP assay to study the mechanism by which the estrogen receptor-alpha/p300 complex activates the BRCA-1 promoter and the repressive effects of p53
Thu Sep 01 00:00:00 EDT 2005
Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation.
Cancer research
Kirma N,Luthra R,Jones J,Liu YG,Nair HB,Mandava U,Tekmal RR
MA5-13062 was used in western blot to study the roles of CSF-1 and its receptor c-fms in hyperplasia and tumor formation
Tue Jun 15 00:00:00 EDT 2004
Context-dependent regulation of GATA-1 by friend of GATA-1.
Proceedings of the National Academy of Sciences of the United States of America
Letting DL,Chen YY,Rakowski C,Reedy S,Blobel GA
MA5-13062 was used in ChIP assay to investigate the regulation of GATA-1 function under different conditions
Tue Jan 13 00:00:00 EST 2004
Molecular mechanism of estrogen receptor (ER)alpha-specific, estradiol-dependent expression of the progesterone receptor (PR) B-isoform.
The Journal of steroid biochemistry and molecular biology
Flötotto T,Niederacher D,Hohmann D,Heimerzheim T,Dall P,Djahansouzi S,Bender HG,Hanstein B
MA5-13062 was used in western blot to study estrogen receptor alpha-dependent upregulation of progesterone receptor-B expression by estradiol
Sun Feb 01 00:00:00 EST 2004
Estrogen response element and the promoter context of the human and mouse lactoferrin genes influence estrogen receptor alpha-mediated transactivation activity in mammary gland cells.
Journal of molecular endocrinology
Stokes K,Alston-Mills B,Teng C
MA5-13062 was used in EMSA to study the differential estrogen responses of the human and mouse lactoferrin overlapping chicken ovalbumin upstream promoter/ERE sequences
Fri Oct 01 00:00:00 EDT 2004
Inhibition of serum-stimulated mitogen activated protein kinase by 1alpha,25(OH)2-vitamin D3 in MCF-7 breast cancer cells.
Journal of cellular biochemistry
Capiati DA,Rossi AM,Picotto G,Benassati S,Boland RL
MA5-13062 was used in western blot to study the mechanism by which 1-alpha, 25-dihydroxyvitamin D3 rapidly inhibits the serum-induced activation of ERK-1 and ERK-2 MAP kinases
Fri Oct 01 00:00:00 EDT 2004
Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line.
Cancer research
DiRenzo J,Signoretti S,Nakamura N,Rivera-Gonzalez R,Sellers W,Loda M,Brown M
MA5-13062 was used in immunohistochemistry to study the growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line
Tue Jan 01 00:00:00 EST 2002
Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.
Cancer research
Kirma N,Gill K,Mandava U,Tekmal RR
MA5-13062 was used in western blot to study the role of aromatase in the biochemical pathways leading to mammary tumorigenesis in transgenic mice
Thu Mar 01 00:00:00 EST 2001
A therapeutic target for hormone-independent estrogen receptor-positive breast cancers.
Molecular medicine (Cambridge, Mass.)
Biswas DK,Cruz A,Pettit N,Mutter GL,Pardee AB
MA5-13062 was used in western blot to study estrogen receptor variants as therapeutic targets for hormone-independent estrogen receptor-positive breast cancers
Mon Jan 01 00:00:00 EST 2001
Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
The Biochemical journal
Schlegel A,Wang C,Pestell RG,Lisanti MP
MA5-13062 was used in immunoprecipitation to investigate the activation of oestrogen receptor alpha by caveolin-1
Mon Oct 01 00:00:00 EDT 2001
Progesterone receptor isoforms expression pattern in human astrocytomas.
Brain research bulletin
González-Agüero G,Ondarza R,Gamboa-Domínguez A,Cerbón MA,Camacho-Arroyo I
MA5-13062 was used in immunohistochemistry to study the expression of different progesterone receptor isoforms in human astrocytomas
Sat Sep 01 00:00:00 EDT 2001
Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF).
The Journal of steroid biochemistry and molecular biology
Klinge CM
MA5-13062 was used in western blot to study the role of estrogen receptor ligand and estrogen response element sequence in the interaction with COUP-TF
Mon Nov 01 00:00:00 EST 1999
17 Beta-estradiol increases VEGF receptor-2 and promotes DNA synthesis in retinal microvascular endothelial cells.
Investigative ophthalmology & visual science
Suzuma I,Mandai M,Takagi H,Suzuma K,Otani A,Oh H,Kobayashi K,Honda Y
MA5-13062 was used in western blot to study the effect of 17-beta-estradiol on VEGF receptor-2 expression and DNA synthesis in retinal microvascular endothelial cells
Sun Aug 01 00:00:00 EDT 1999
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1.
Genes & development
Zwijsen RM,Buckle RS,Hijmans EM,Loomans CJ,Bernards R
MA5-13062 was used in immunoprecipitation to study the role of cyclin D1 in ligand-independent recruitment of steroid receptor coactivators to estrogen receptors
Sun Nov 15 00:00:00 EST 1998
Classification of breast cancer cells on the basis of a functional assay for estrogen receptor.
Molecular medicine (Cambridge, Mass.)
Biswas DK,Averboukh L,Sheng S,Martin K,Ewaniuk DS,Jawde TF,Wang F,Pardee AB
MA5-13062 was used in EMSA and immunocytochemistry to study the classification of estrogen receptor-positive breast tumor cells on the basis of a functional estrogen receptor assay
Wed Jul 01 00:00:00 EDT 1998
Calmodulin is essential for estrogen receptor interaction with its motif and activation of responsive promoter.
The Journal of biological chemistry
Biswas DK,Reddy PV,Pickard M,Makkad B,Pettit N,Pardee AB
MA5-13062 was used in blocking or activating experiment, immunoprecipitation, and western blot to study the role of calmodulin in the formation of the active estrogen receptor complex
Fri Dec 11 00:00:00 EST 1998