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MA5-13822 targets IGF-1 Receptor beta in WB applications and shows reactivity with Human and Rat samples.
The MA5-13822 immunogen is a 15-mer peptide corresponding to aa 1323-1337 (Tyr-RKNERALPLPQSSTC) from the C-terminal of beta-subunit of human IGF-1R.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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