This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MEIS1, also known as Homeobox protein Meis1, is a nuclear protein belonging to the TALE/MEIS homeobox family with a homeobox DNA-binding domain. It acts as a transcriptional regulator of PAX6 (Paired box protein Pax-6). It is a protein required for hematopoiesis, megakaryocyte lineage development and vascular patterning. Expression is seen at low levels in normal immunohepatopoietic tissues, and in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. It is also expressed at high levels in the cerebellum.
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Protein Aliases: Homeobox protein Meis1; leukemogenic homolog protein; Meis homeobox 1; MEIS1; Meis1, myeloid ecotropic viral integration site 1 homolog; MGC43380; Myeloid ecotropic viral integration site 1; WUGSC:H_NH0444B04.1
Gene Aliases: C530044H18Rik; Evi8; MEIS1